Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 1134389..1134930 Replicon chromosome
Accession NZ_CP029255
Organism Flavobacterium crocinum strain HYN0056

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HYN56_RS05230 Protein ID WP_109191215.1
Coordinates 1134634..1134930 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HYN56_RS05225 Protein ID WP_109191214.1
Coordinates 1134389..1134637 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYN56_RS05195 1129935..1130438 - 504 WP_109191209.1 phage tail protein -
HYN56_RS05200 1130462..1130971 - 510 WP_109191210.1 phage tail protein -
HYN56_RS05205 1131004..1131669 - 666 WP_109191211.1 hypothetical protein -
HYN56_RS05210 1131895..1132074 - 180 WP_008465789.1 twin-arginine translocase TatA/TatE family subunit -
HYN56_RS05215 1132289..1132792 + 504 WP_109191212.1 peptidase -
HYN56_RS05220 1132804..1134288 + 1485 WP_109191213.1 GH3 auxin-responsive promoter family protein -
HYN56_RS05225 1134389..1134637 + 249 WP_109191214.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HYN56_RS05230 1134634..1134930 + 297 WP_109191215.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HYN56_RS05235 1134992..1136671 + 1680 WP_109191216.1 hypothetical protein -
HYN56_RS05240 1136680..1137675 + 996 WP_109191217.1 hypothetical protein -
HYN56_RS05245 1137693..1138208 + 516 WP_109191218.1 hypothetical protein -
HYN56_RS05250 1138240..1139445 + 1206 WP_109191219.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11920.78 Da        Isoelectric Point: 8.0401

>T105362 WP_109191215.1 NZ_CP029255:1134634-1134930 [Flavobacterium crocinum]
MNYKISIEASYDLEKIWLYTFDTWSTEQADRYLKLILDEIEYLCSKPNSGKDFSHIRKGYFRTKVKSHLIFYKINVKQNE
IEIIRVLHQMMDIENHLK

Download         Length: 297 bp

>T105362 NZ_CP029255:1134634-1134930 [Flavobacterium crocinum]
ATGAATTATAAGATAAGTATAGAAGCATCTTATGATTTAGAAAAAATTTGGCTTTATACTTTTGATACTTGGTCTACTGA
ACAAGCAGATAGATACTTAAAGTTGATATTGGATGAAATCGAATACCTGTGTTCAAAACCTAATTCAGGAAAAGATTTTA
GTCATATCAGAAAAGGTTATTTTAGAACCAAAGTAAAATCACATTTAATATTTTATAAAATAAACGTCAAACAAAACGAA
ATAGAAATTATTAGAGTTTTGCATCAAATGATGGACATTGAAAATCATCTTAAATAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9528.87 Da        Isoelectric Point: 9.6566

>AT105362 WP_109191214.1 NZ_CP029255:1134389-1134637 [Flavobacterium crocinum]
MAKNTSILLGDYFDNFINSQVKTGRFTSASEVIRAALRMFEQEQTKSEELIKELKKGEKSGFVKDFDRESFLTNLHEKHL
KK

Download         Length: 249 bp

>AT105362 NZ_CP029255:1134389-1134637 [Flavobacterium crocinum]
ATGGCAAAGAATACGTCAATATTATTAGGAGACTATTTTGATAATTTTATTAATTCACAAGTTAAAACTGGCCGATTCAC
ATCTGCAAGTGAAGTAATTCGAGCCGCATTACGAATGTTTGAACAAGAACAAACCAAAAGTGAAGAACTAATAAAGGAAT
TAAAAAAAGGAGAAAAATCGGGATTTGTAAAGGATTTTGATCGCGAATCTTTTCTAACAAATCTTCACGAAAAACATCTT
AAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References