Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2044108..2044379 Replicon chromosome
Accession NZ_CP029242
Organism Escherichia coli strain ECCRA-119

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2044238..2044341 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2044108..2044379 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7235_RS10575 2040663..2041325 - 663 WP_000944256.1 exodeoxyribonuclease X -
C7235_RS10580 2041349..2042005 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C7235_RS10585 2042107..2042337 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C7235_RS10590 2042476..2042850 + 375 WP_000204699.1 CopC domain-containing protein YobA -
C7235_RS10595 2042854..2043726 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
C7235_RS10600 2043739..2044080 + 342 WP_000976472.1 YebY family protein -
- 2044108..2044379 - 272 - - Antitoxin
- 2044238..2044341 + 104 - - Toxin
C7235_RS10605 2044476..2045132 + 657 WP_000812735.1 protein-serine/threonine phosphatase -
C7235_RS10610 2045133..2045324 - 192 WP_001296140.1 YebW family protein -
C7235_RS10615 2045429..2045665 - 237 WP_001295499.1 DUF1480 family protein -
C7235_RS10620 2045783..2047222 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T105320 NZ_CP029242:2044238-2044341 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT105320 NZ_CP029242:c2044379-2044108 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References