Detailed information of TA system TA105226

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yoeB-relE/YoeB-YefM
• Location: 56485..56987
• Replicon: plasmid pTB101
• Accession: NZ_CP029211
• Organism: Aquabacterium olei strain NBRC 110486

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: DEH84_RS17650
• Protein ID: WP_109038531.1
• Coordinates: 56485..56739 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: DEH84_RS17655
• Protein ID: WP_109038532.1
• Coordinates: 56736..56987 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DEH84_RS19200	52045..53028	+	984	WP_159099048.1	hypothetical protein	-
DEH84_RS19205	53710..54384	+	675	WP_159099049.1	hypothetical protein	-
DEH84_RS19210	54691..55011	+	321	WP_159099050.1	hypothetical protein	-
DEH84_RS17645	55348..56364	-	1017	WP_109038530.1	IS110 family transposase	-
DEH84_RS17650	56485..56739	-	255	WP_109038531.1	Txe/YoeB family addiction module toxin	Toxin
DEH84_RS17655	56736..56987	-	252	WP_109038532.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
DEH84_RS17660	57196..57546	+	351	WP_159099051.1	hypothetical protein	-
DEH84_RS17665	57606..58013	+	408	WP_109038534.1	VOC family protein	-
DEH84_RS17670	58032..58796	-	765	WP_109038535.1	SDR family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..366221	366221

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10142.68 Da
• Isoelectric Point: 9.3050

>T105226 WP_109038531.1 NZ_CP029211:c56739-56485 [Aquabacterium olei]
MKLIFADAAWDDYLYWQQQDRRMVERINKLIKEAQREPFAGIGKPEPLKHALAGYWSRRITDEHRMVYKVDGDSMLIAQL
RYHY

Nucleotide

• Length: 255 bp

>T105226 NZ_CP029211:c56739-56485 [Aquabacterium olei]
ATGAAGTTGATCTTCGCAGATGCCGCATGGGATGACTACCTCTACTGGCAACAACAAGACAGGCGCATGGTTGAGCGCAT
CAACAAGCTGATCAAAGAGGCGCAGCGTGAACCCTTTGCCGGGATCGGTAAACCTGAGCCTTTGAAGCACGCGCTGGCGG
GATATTGGTCCAGAAGAATCACCGACGAACACCGCATGGTTTACAAAGTTGATGGCGATTCAATGCTGATTGCCCAATTG
CGCTACCACTATTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9005.11 Da
• Isoelectric Point: 4.3611

>AT105226 WP_109038532.1 NZ_CP029211:c56987-56736 [Aquabacterium olei]
MDAISYSSARANLASTMDRVCEDHEALIITRNGQQSVVMLSLEDFTALEETAYLLRSPSNAKRLMGAIEQLNAGTGTGRE
LAE

Nucleotide

• Length: 252 bp

>AT105226 NZ_CP029211:c56987-56736 [Aquabacterium olei]
ATGGATGCCATCTCGTACTCGTCTGCTCGCGCCAACTTGGCCAGCACCATGGATCGCGTGTGCGAAGACCATGAAGCCCT
CATCATCACGCGCAACGGCCAACAGTCTGTTGTGATGCTCTCTCTTGAGGACTTCACTGCCCTTGAAGAGACAGCGTACC
TTCTCCGCAGCCCCTCGAACGCGAAACGACTGATGGGCGCGATTGAGCAGTTGAATGCTGGTACTGGCACGGGACGCGAG
CTGGCCGAATGA