Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1927196..1927740 Replicon chromosome
Accession NZ_CP029206
Organism Actinobacillus porcitonsillarum strain 9953L55

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DDU33_RS09295 Protein ID WP_108924843.1
Coordinates 1927196..1927483 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DDU33_RS09300 Protein ID WP_108924844.1
Coordinates 1927492..1927740 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DDU33_RS09275 1922694..1923785 + 1092 WP_108924840.1 glutamate 5-kinase -
DDU33_RS09280 1923809..1924573 + 765 WP_108924841.1 TSUP family transporter -
DDU33_RS09285 1924574..1925209 + 636 WP_005818971.1 endonuclease III -
DDU33_RS09295 1927196..1927483 - 288 WP_108924843.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DDU33_RS09300 1927492..1927740 - 249 WP_108924844.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DDU33_RS09305 1928018..1928395 - 378 WP_108924845.1 hypothetical protein -
DDU33_RS09310 1928417..1929421 - 1005 WP_108924846.1 hypothetical protein -
DDU33_RS09315 1929469..1930146 - 678 WP_108924847.1 hypothetical protein -
DDU33_RS09320 1930164..1931036 - 873 WP_108924848.1 hypothetical protein -
DDU33_RS09325 1931049..1932563 - 1515 WP_108924849.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-85)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-70)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11091.93 Da        Isoelectric Point: 9.8943

>T105221 WP_108924843.1 NZ_CP029206:c1927483-1927196 [Actinobacillus porcitonsillarum]
MTYSIKVHDDFVEELNKLDTAIRTQLRKKLDKVVENPHIPKNRLAGGLHNCYKIKLRRAGVRLVYQVNDDEIYILLLTVG
KRADNEVYETALKRL

Download         Length: 288 bp

>T105221 NZ_CP029206:c1927483-1927196 [Actinobacillus porcitonsillarum]
ATGACCTATTCAATTAAGGTTCACGATGATTTTGTCGAAGAGTTGAATAAACTCGATACTGCAATTAGAACACAGTTGCG
TAAAAAACTCGACAAAGTAGTTGAAAATCCGCATATTCCAAAGAACCGATTAGCAGGCGGATTGCATAATTGTTACAAAA
TTAAACTCAGACGAGCAGGTGTTCGTTTGGTTTATCAAGTTAATGATGATGAAATTTATATCCTTTTACTTACGGTAGGT
AAAAGAGCGGATAATGAAGTTTATGAAACGGCATTAAAACGGTTGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9274.57 Da        Isoelectric Point: 4.4091

>AT105221 WP_108924844.1 NZ_CP029206:c1927740-1927492 [Actinobacillus porcitonsillarum]
MSNLNIRIDDVVKKQAFEAFDNLGISPSDAIRSFLAYVAETGRMPIKQIIVSDEDADLYALVKQRLNEPEKIKNTTLDEL
FS

Download         Length: 249 bp

>AT105221 NZ_CP029206:c1927740-1927492 [Actinobacillus porcitonsillarum]
ATGTCAAACTTAAATATCCGTATTGATGATGTGGTAAAAAAACAAGCATTTGAGGCTTTTGATAACTTAGGGATCAGCCC
ATCAGATGCTATACGTTCATTCTTAGCGTATGTAGCGGAAACTGGTAGAATGCCAATCAAGCAAATTATTGTATCTGACG
AAGATGCGGATTTATATGCGTTGGTTAAACAGCGTTTAAATGAACCTGAAAAAATCAAAAACACAACCCTTGATGAATTA
TTCTCATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References