Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1584962..1585469 Replicon chromosome
Accession NZ_CP029186
Organism Flavobacterium album strain HYN0059

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HYN59_RS06900 Protein ID WP_108777573.1
Coordinates 1584962..1585225 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HYN59_RS06905 Protein ID WP_108777574.1
Coordinates 1585215..1585469 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYN59_RS06875 1580320..1580826 + 507 WP_108777568.1 SMI1/KNR4 family protein -
HYN59_RS06880 1580894..1582519 + 1626 WP_108777569.1 hypothetical protein -
HYN59_RS06885 1582601..1583311 - 711 WP_108777570.1 hypothetical protein -
HYN59_RS06890 1583328..1583711 - 384 WP_108777571.1 DUF4878 domain-containing protein -
HYN59_RS06895 1583776..1584942 - 1167 WP_108777572.1 formate-dependent phosphoribosylglycinamide formyltransferase -
HYN59_RS06900 1584962..1585225 - 264 WP_108777573.1 Txe/YoeB family addiction module toxin Toxin
HYN59_RS06905 1585215..1585469 - 255 WP_108777574.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HYN59_RS06910 1585566..1586750 - 1185 WP_108777575.1 pyridoxal phosphate-dependent aminotransferase -
HYN59_RS06915 1586785..1587879 - 1095 WP_108777576.1 acyl-CoA desaturase -
HYN59_RS06920 1587986..1588615 + 630 WP_108777577.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
HYN59_RS06925 1588664..1589707 - 1044 WP_181369525.1 Omp28-related outer membrane protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10343.68 Da        Isoelectric Point: 7.1971

>T105182 WP_108777573.1 NZ_CP029186:c1585225-1584962 [Flavobacterium album]
MSFSIEFTDTALEDYNFWKKTNNTRILNKIKSLLANMQETPFTGIGQPEALRYELSGYYSRRINQEHRIVYTVEESTIYV
IQLRGHY

Download         Length: 264 bp

>T105182 NZ_CP029186:c1585225-1584962 [Flavobacterium album]
ATGAGCTTTAGCATCGAGTTTACCGATACGGCATTGGAAGATTATAATTTTTGGAAAAAAACCAATAATACAAGGATTCT
AAACAAAATAAAATCGCTGCTGGCCAATATGCAGGAAACGCCTTTTACAGGCATCGGGCAGCCCGAAGCTTTGCGATATG
AGCTTAGCGGATATTACAGCCGCAGGATCAATCAGGAACACCGAATAGTATATACGGTAGAAGAAAGTACTATTTATGTA
ATACAATTGAGAGGTCATTACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9649.03 Da        Isoelectric Point: 5.8506

>AT105182 WP_108777574.1 NZ_CP029186:c1585469-1585215 [Flavobacterium album]
MKTISITDLRKNLKETLDTVIDDNQEIIVHRPNNEDVVLISLSDYNSLNETLKLLSSEKNRSRLLLGKEQLKQGKTTKIN
LDEL

Download         Length: 255 bp

>AT105182 NZ_CP029186:c1585469-1585215 [Flavobacterium album]
ATGAAAACAATAAGTATTACAGATCTCAGAAAGAATTTAAAAGAAACGCTTGATACTGTTATCGATGATAATCAGGAGAT
CATAGTGCATCGTCCAAATAATGAAGATGTAGTGCTTATTTCATTATCGGATTATAATTCGCTGAATGAGACACTAAAAC
TGCTTTCTTCCGAAAAAAACCGTTCACGCCTGCTGTTAGGTAAAGAACAATTAAAGCAGGGCAAAACAACAAAAATCAAT
TTGGATGAGCTTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References