Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 2316822..2317375 Replicon chromosome
Accession NZ_CP029185
Organism Limnobaculum parvum strain HYN0051

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag HYN51_RS09740 Protein ID WP_108899854.1
Coordinates 2316822..2317130 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag HYN51_RS09745 Protein ID WP_108899855.1
Coordinates 2317133..2317375 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYN51_RS09715 2312628..2313536 - 909 WP_108902017.1 sulfate adenylyltransferase subunit CysD -
HYN51_RS09720 2313569..2315005 - 1437 WP_108899850.1 siroheme synthase CysG -
HYN51_RS09725 2315198..2316115 + 918 WP_108899851.1 dienelactone hydrolase family protein -
HYN51_RS09730 2316096..2316212 - 117 WP_108899852.1 CcdB family protein -
HYN51_RS09735 2316407..2316670 + 264 WP_108899853.1 hypothetical protein -
HYN51_RS09740 2316822..2317130 - 309 WP_108899854.1 CcdB family protein Toxin
HYN51_RS09745 2317133..2317375 - 243 WP_108899855.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
HYN51_RS09750 2317983..2318717 - 735 WP_108899856.1 phosphoadenylyl-sulfate reductase -
HYN51_RS09755 2318727..2320424 - 1698 WP_108899857.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
HYN51_RS09760 2320424..2322229 - 1806 WP_108899858.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(10-80)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11893.76 Da        Isoelectric Point: 7.2401

>T105180 WP_108899854.1 NZ_CP029185:c2317130-2316822 [Limnobaculum parvum]
VQYTVYRNTGNNKDYPYLLNVQSDLIDALTTRWVIPLFPRRRFKGKVPQHLCPILSIGEVEYLLMTHEMASVRKSMLGDE
VCQAQHYRDEIKAAIDFMIDGF

Download         Length: 309 bp

>T105180 NZ_CP029185:c2317130-2316822 [Limnobaculum parvum]
GTGCAATATACTGTCTATCGTAATACGGGTAATAACAAGGATTACCCGTACTTATTGAATGTACAAAGTGACCTGATTGA
TGCGTTGACAACGCGATGGGTGATTCCACTCTTCCCCCGTCGCCGATTTAAAGGAAAGGTCCCTCAACACTTATGCCCGA
TACTGAGTATTGGGGAAGTTGAGTACTTATTGATGACGCATGAGATGGCCAGCGTTCGCAAAAGTATGCTGGGTGACGAA
GTGTGCCAGGCCCAGCATTATCGCGATGAGATTAAAGCCGCGATTGATTTTATGATTGATGGTTTTTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8934.17 Da        Isoelectric Point: 7.2013

>AT105180 WP_108899855.1 NZ_CP029185:c2317375-2317133 [Limnobaculum parvum]
MTKTHAKITKKTVSVTLDPVLYQKARDMGINLSAVLTQAIEAQLQAASAAQWKHENRQAMEELNRISDESGLLSDEYKAF

Download         Length: 243 bp

>AT105180 NZ_CP029185:c2317375-2317133 [Limnobaculum parvum]
ATGACAAAAACCCATGCAAAAATAACCAAAAAGACGGTCAGTGTGACGTTGGATCCAGTTTTGTATCAAAAGGCTCGCGA
TATGGGTATCAATTTATCAGCAGTATTGACTCAAGCCATTGAGGCACAGTTACAGGCAGCATCTGCTGCTCAATGGAAGC
ATGAAAACCGGCAGGCGATGGAAGAGCTAAACCGGATTAGTGATGAGAGCGGCTTACTTTCCGATGAATATAAGGCATTT
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References