Detailed information of TA system TA105179

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 824409..824936
• Replicon: chromosome
• Accession: NZ_CP029185
• Organism: Limnobaculum parvum strain HYN0051

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HYN51_RS03050
• Protein ID: WP_108901494.1
• Coordinates: 824409..824684 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HYN51_RS03055
• Protein ID: WP_108902138.1
• Coordinates: 824688..824936 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HYN51_RS03020	819616..819948	+	333	WP_108901489.1	hypothetical protein	-
HYN51_RS03025	820014..820601	+	588	WP_108902137.1	hypothetical protein	-
HYN51_RS03030	820594..820908	+	315	WP_108901490.1	hypothetical protein	-
HYN51_RS03035	820892..821203	+	312	WP_108901491.1	YtxH domain-containing protein	-
HYN51_RS03040	821211..823280	+	2070	WP_108901492.1	heavy metal translocating P-type ATPase	-
HYN51_RS03045	823654..824253	-	600	WP_108901493.1	histidine phosphatase family protein	-
HYN51_RS03050	824409..824684	-	276	WP_108901494.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HYN51_RS03055	824688..824936	-	249	WP_108902138.1	ribbon-helix-helix domain-containing protein	Antitoxin
HYN51_RS03060	825215..826216	-	1002	WP_108901495.1	HTH-type transcriptional regulator GalR	-
HYN51_RS03065	826627..828783	+	2157	WP_108901496.1	bifunctional acyl-ACP--phospholipid O-acyltransferase/long-chain-fatty-acid--ACP ligase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-42)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10905.22 Da
• Isoelectric Point: 5.1110

>T105179 WP_108901494.1 NZ_CP029185:c824684-824409 [Limnobaculum parvum]
MEIYWTLKAQDDLERIYRFALQYNRQHAVDVLDRLITGSASLTAHPAIGVQQARYDPREVRKVLFDDYEVHYEVKDNDIF
IVDLWHTKEDH

Nucleotide

• Length: 276 bp

>T105179 NZ_CP029185:c824684-824409 [Limnobaculum parvum]
ATGGAAATTTACTGGACGCTTAAAGCTCAGGACGATCTGGAGCGTATCTATCGTTTTGCCCTTCAATACAACCGCCAACA
TGCCGTTGATGTTTTAGACCGCCTGATAACGGGAAGCGCTAGCCTTACAGCGCATCCGGCTATTGGCGTACAGCAAGCGC
GGTATGACCCTCGCGAAGTGAGGAAGGTTTTGTTCGACGACTACGAGGTCCACTACGAAGTCAAAGATAATGACATTTTC
ATCGTGGATCTCTGGCATACGAAAGAGGATCACTGA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9186.58 Da
• Isoelectric Point: 6.7259

>AT105179 WP_108902138.1 NZ_CP029185:c824936-824688 [Limnobaculum parvum]
MGSHSKQTISAQIPVELALAVEELAIELDRSKSWIIKEALLTMLAERERRHQSVLKGLTDVDTGRVVSHSDMVDFADRLK
KS

Nucleotide

• Length: 249 bp

>AT105179 NZ_CP029185:c824936-824688 [Limnobaculum parvum]
ATGGGATCTCATAGTAAGCAAACCATCAGCGCCCAAATTCCCGTCGAGCTGGCCCTTGCCGTTGAGGAGCTGGCTATAGA
GCTGGATCGTTCAAAAAGCTGGATTATAAAGGAAGCATTACTCACCATGCTGGCAGAAAGAGAGCGGAGACATCAAAGCG
TGCTGAAGGGCCTTACTGACGTCGATACAGGTCGTGTAGTTAGTCATTCGGACATGGTGGATTTTGCTGACCGTCTAAAG
AAATCCTGA