Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 824409..824936 Replicon chromosome
Accession NZ_CP029185
Organism Limnobaculum parvum strain HYN0051

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HYN51_RS03050 Protein ID WP_108901494.1
Coordinates 824409..824684 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HYN51_RS03055 Protein ID WP_108902138.1
Coordinates 824688..824936 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYN51_RS03020 819616..819948 + 333 WP_108901489.1 hypothetical protein -
HYN51_RS03025 820014..820601 + 588 WP_108902137.1 hypothetical protein -
HYN51_RS03030 820594..820908 + 315 WP_108901490.1 hypothetical protein -
HYN51_RS03035 820892..821203 + 312 WP_108901491.1 YtxH domain-containing protein -
HYN51_RS03040 821211..823280 + 2070 WP_108901492.1 heavy metal translocating P-type ATPase -
HYN51_RS03045 823654..824253 - 600 WP_108901493.1 histidine phosphatase family protein -
HYN51_RS03050 824409..824684 - 276 WP_108901494.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HYN51_RS03055 824688..824936 - 249 WP_108902138.1 ribbon-helix-helix domain-containing protein Antitoxin
HYN51_RS03060 825215..826216 - 1002 WP_108901495.1 HTH-type transcriptional regulator GalR -
HYN51_RS03065 826627..828783 + 2157 WP_108901496.1 bifunctional acyl-ACP--phospholipid O-acyltransferase/long-chain-fatty-acid--ACP ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-42)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10905.22 Da        Isoelectric Point: 5.1110

>T105179 WP_108901494.1 NZ_CP029185:c824684-824409 [Limnobaculum parvum]
MEIYWTLKAQDDLERIYRFALQYNRQHAVDVLDRLITGSASLTAHPAIGVQQARYDPREVRKVLFDDYEVHYEVKDNDIF
IVDLWHTKEDH

Download         Length: 276 bp

>T105179 NZ_CP029185:c824684-824409 [Limnobaculum parvum]
ATGGAAATTTACTGGACGCTTAAAGCTCAGGACGATCTGGAGCGTATCTATCGTTTTGCCCTTCAATACAACCGCCAACA
TGCCGTTGATGTTTTAGACCGCCTGATAACGGGAAGCGCTAGCCTTACAGCGCATCCGGCTATTGGCGTACAGCAAGCGC
GGTATGACCCTCGCGAAGTGAGGAAGGTTTTGTTCGACGACTACGAGGTCCACTACGAAGTCAAAGATAATGACATTTTC
ATCGTGGATCTCTGGCATACGAAAGAGGATCACTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9186.58 Da        Isoelectric Point: 6.7259

>AT105179 WP_108902138.1 NZ_CP029185:c824936-824688 [Limnobaculum parvum]
MGSHSKQTISAQIPVELALAVEELAIELDRSKSWIIKEALLTMLAERERRHQSVLKGLTDVDTGRVVSHSDMVDFADRLK
KS

Download         Length: 249 bp

>AT105179 NZ_CP029185:c824936-824688 [Limnobaculum parvum]
ATGGGATCTCATAGTAAGCAAACCATCAGCGCCCAAATTCCCGTCGAGCTGGCCCTTGCCGTTGAGGAGCTGGCTATAGA
GCTGGATCGTTCAAAAAGCTGGATTATAAAGGAAGCATTACTCACCATGCTGGCAGAAAGAGAGCGGAGACATCAAAGCG
TGCTGAAGGGCCTTACTGACGTCGATACAGGTCGTGTAGTTAGTCATTCGGACATGGTGGATTTTGCTGACCGTCTAAAG
AAATCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References