Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/HicA-HicB |
Location | 626375..627016 | Replicon | chromosome |
Accession | NZ_CP029185 | ||
Organism | Limnobaculum parvum strain HYN0051 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | - |
Locus tag | HYN51_RS02210 | Protein ID | WP_108901346.1 |
Coordinates | 626375..626557 (+) | Length | 61 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | - |
Locus tag | HYN51_RS02215 | Protein ID | WP_108901347.1 |
Coordinates | 626576..627016 (+) | Length | 147 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HYN51_RS02180 | 621507..622913 | + | 1407 | WP_108901340.1 | PTS ascorbate transporter subunit IIC | - |
HYN51_RS02185 | 622932..623237 | + | 306 | WP_108901341.1 | PTS ascorbate transporter subunit IIB | - |
HYN51_RS02190 | 623247..623705 | + | 459 | WP_108901342.1 | PTS ascorbate transporter subunit IIA | - |
HYN51_RS02195 | 623753..624409 | + | 657 | WP_108901343.1 | 3-keto-L-gulonate-6-phosphate decarboxylase UlaD | - |
HYN51_RS02200 | 624419..625279 | + | 861 | WP_108901344.1 | L-ribulose-5-phosphate 3-epimerase | - |
HYN51_RS02205 | 625279..625968 | + | 690 | WP_108901345.1 | L-ribulose-5-phosphate 4-epimerase | - |
HYN51_RS02210 | 626375..626557 | + | 183 | WP_108901346.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
HYN51_RS02215 | 626576..627016 | + | 441 | WP_108901347.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
HYN51_RS02220 | 627060..627989 | - | 930 | WP_108901348.1 | 2-dehydropantoate 2-reductase | - |
HYN51_RS02225 | 628225..628941 | + | 717 | WP_108901349.1 | phosphatase PAP2 family protein | - |
HYN51_RS02230 | 628966..629553 | + | 588 | WP_108901350.1 | undecaprenyl-diphosphate phosphatase | - |
HYN51_RS02235 | 630010..631320 | + | 1311 | WP_108901351.1 | collagen-like triple helix repeat-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 61 a.a. Molecular weight: 6803.92 Da Isoelectric Point: 11.4114
>T105178 WP_108901346.1 NZ_CP029185:626375-626557 [Limnobaculum parvum]
MKSSDLIKELRAAGCEWRRHNGGSHQIWWSPITKKTFPVPHPKKNLPEGTVRSIKRAAGI
MKSSDLIKELRAAGCEWRRHNGGSHQIWWSPITKKTFPVPHPKKNLPEGTVRSIKRAAGI
Download Length: 183 bp
>T105178 NZ_CP029185:626375-626557 [Limnobaculum parvum]
ATGAAATCATCGGATTTGATTAAAGAACTTCGGGCTGCTGGGTGTGAATGGCGGCGGCATAATGGAGGAAGCCACCAGAT
ATGGTGGTCTCCGATAACGAAAAAAACATTTCCAGTCCCTCATCCTAAAAAGAATTTGCCTGAGGGCACCGTTAGATCGA
TCAAAAGAGCGGCTGGAATTTAG
ATGAAATCATCGGATTTGATTAAAGAACTTCGGGCTGCTGGGTGTGAATGGCGGCGGCATAATGGAGGAAGCCACCAGAT
ATGGTGGTCTCCGATAACGAAAAAAACATTTCCAGTCCCTCATCCTAAAAAGAATTTGCCTGAGGGCACCGTTAGATCGA
TCAAAAGAGCGGCTGGAATTTAG
Antitoxin
Download Length: 147 a.a. Molecular weight: 16442.66 Da Isoelectric Point: 4.2618
>AT105178 WP_108901347.1 NZ_CP029185:626576-627016 [Limnobaculum parvum]
MLFSIAVEVPQDEQTAYGLTVPALCNEDYGCFSAADCVEDVAGMAREAILLTITDMIESGRYSLAQIKDLGPLVYQKTHT
EFDGQQWFVIEVDLSELEGKPQRINISLPDVLIRRIDSRVKTQDDYRDRSHFLAVAAKNELLRMEG
MLFSIAVEVPQDEQTAYGLTVPALCNEDYGCFSAADCVEDVAGMAREAILLTITDMIESGRYSLAQIKDLGPLVYQKTHT
EFDGQQWFVIEVDLSELEGKPQRINISLPDVLIRRIDSRVKTQDDYRDRSHFLAVAAKNELLRMEG
Download Length: 441 bp
>AT105178 NZ_CP029185:626576-627016 [Limnobaculum parvum]
ATGTTATTTTCTATTGCTGTTGAAGTACCACAAGATGAGCAGACGGCTTATGGTCTAACTGTGCCTGCTTTATGTAACGA
AGATTATGGCTGTTTTTCTGCGGCAGACTGCGTAGAAGATGTGGCCGGAATGGCCCGGGAGGCCATTTTACTCACCATCA
CTGATATGATTGAATCAGGGCGCTATTCTTTAGCGCAAATTAAAGATCTTGGTCCGTTGGTTTATCAGAAAACCCATACT
GAATTTGATGGACAACAATGGTTTGTGATTGAGGTTGATTTGTCGGAGCTGGAAGGAAAACCACAGCGGATTAATATTTC
GCTACCGGATGTGTTAATTCGTCGAATTGATTCACGTGTTAAAACTCAGGATGATTACCGCGACCGTAGCCATTTTCTGG
CCGTTGCGGCAAAAAATGAATTATTAAGGATGGAAGGGTAA
ATGTTATTTTCTATTGCTGTTGAAGTACCACAAGATGAGCAGACGGCTTATGGTCTAACTGTGCCTGCTTTATGTAACGA
AGATTATGGCTGTTTTTCTGCGGCAGACTGCGTAGAAGATGTGGCCGGAATGGCCCGGGAGGCCATTTTACTCACCATCA
CTGATATGATTGAATCAGGGCGCTATTCTTTAGCGCAAATTAAAGATCTTGGTCCGTTGGTTTATCAGAAAACCCATACT
GAATTTGATGGACAACAATGGTTTGTGATTGAGGTTGATTTGTCGGAGCTGGAAGGAAAACCACAGCGGATTAATATTTC
GCTACCGGATGTGTTAATTCGTCGAATTGATTCACGTGTTAAAACTCAGGATGATTACCGCGACCGTAGCCATTTTCTGG
CCGTTGCGGCAAAAAATGAATTATTAAGGATGGAAGGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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