Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 626375..627016 Replicon chromosome
Accession NZ_CP029185
Organism Limnobaculum parvum strain HYN0051

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag HYN51_RS02210 Protein ID WP_108901346.1
Coordinates 626375..626557 (+) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag HYN51_RS02215 Protein ID WP_108901347.1
Coordinates 626576..627016 (+) Length 147 a.a.

Genomic Context

HYN51_RS02180HYN51_RS02185HYN51_RS02190HYN51_RS02195HYN51_RS02200HYN51_RS02205HYN51_RS02210HYN51_RS02215HYN51_RS02225HYN51_RS02230HYN51_RS02235HYN51_RS02220
Location: 621507..622913 (1407 bp)
Type: Others
Protein ID: WP_108901340.1
Location: 622932..623237 (306 bp)
Type: Others
Protein ID: WP_108901341.1
Location: 623247..623705 (459 bp)
Type: Others
Protein ID: WP_108901342.1
Location: 623753..624409 (657 bp)
Type: Others
Protein ID: WP_108901343.1
Location: 624419..625279 (861 bp)
Type: Others
Protein ID: WP_108901344.1
Location: 625279..625968 (690 bp)
Type: Others
Protein ID: WP_108901345.1
Location: 626375..626557 (183 bp)
Type: Toxin
Protein ID: WP_108901346.1
Location: 626576..627016 (441 bp)
Type: Antitoxin
Protein ID: WP_108901347.1
Location: 628225..628941 (717 bp)
Type: Others
Protein ID: WP_108901349.1
Location: 628966..629553 (588 bp)
Type: Others
Protein ID: WP_108901350.1
Location: 630010..631320 (1311 bp)
Type: Others
Protein ID: WP_108901351.1
Location: 627060..627989 (930 bp)
Type: Others
Protein ID: WP_108901348.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HYN51_RS02180621507..622913+1407WP_108901340.1PTS ascorbate transporter subunit IIC-
HYN51_RS02185622932..623237+306WP_108901341.1PTS ascorbate transporter subunit IIB-
HYN51_RS02190623247..623705+459WP_108901342.1PTS ascorbate transporter subunit IIA-
HYN51_RS02195623753..624409+657WP_108901343.13-keto-L-gulonate-6-phosphate decarboxylase UlaD-
HYN51_RS02200624419..625279+861WP_108901344.1L-ribulose-5-phosphate 3-epimerase-
HYN51_RS02205625279..625968+690WP_108901345.1L-ribulose-5-phosphate 4-epimerase-
HYN51_RS02210626375..626557+183WP_108901346.1type II toxin-antitoxin system HicA family toxinToxin
HYN51_RS02215626576..627016+441WP_108901347.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
HYN51_RS02220627060..627989-930WP_108901348.12-dehydropantoate 2-reductase-
HYN51_RS02225628225..628941+717WP_108901349.1phosphatase PAP2 family protein-
HYN51_RS02230628966..629553+588WP_108901350.1undecaprenyl-diphosphate phosphatase-
HYN51_RS02235630010..631320+1311WP_108901351.1collagen-like triple helix repeat-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(4-60)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-137)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6803.92 Da        Isoelectric Point: 11.4114

>T105178 WP_108901346.1 NZ_CP029185:626375-626557 [Limnobaculum parvum]
MKSSDLIKELRAAGCEWRRHNGGSHQIWWSPITKKTFPVPHPKKNLPEGTVRSIKRAAGI

Download         Length: 183 bp

>T105178 NZ_CP029185:626375-626557 [Limnobaculum parvum]
ATGAAATCATCGGATTTGATTAAAGAACTTCGGGCTGCTGGGTGTGAATGGCGGCGGCATAATGGAGGAAGCCACCAGAT
ATGGTGGTCTCCGATAACGAAAAAAACATTTCCAGTCCCTCATCCTAAAAAGAATTTGCCTGAGGGCACCGTTAGATCGA
TCAAAAGAGCGGCTGGAATTTAG

Antitoxin


Download         Length: 147 a.a.        Molecular weight: 16442.66 Da        Isoelectric Point: 4.2618

>AT105178 WP_108901347.1 NZ_CP029185:626576-627016 [Limnobaculum parvum]
MLFSIAVEVPQDEQTAYGLTVPALCNEDYGCFSAADCVEDVAGMAREAILLTITDMIESGRYSLAQIKDLGPLVYQKTHT
EFDGQQWFVIEVDLSELEGKPQRINISLPDVLIRRIDSRVKTQDDYRDRSHFLAVAAKNELLRMEG

Download         Length: 441 bp

>AT105178 NZ_CP029185:626576-627016 [Limnobaculum parvum]
ATGTTATTTTCTATTGCTGTTGAAGTACCACAAGATGAGCAGACGGCTTATGGTCTAACTGTGCCTGCTTTATGTAACGA
AGATTATGGCTGTTTTTCTGCGGCAGACTGCGTAGAAGATGTGGCCGGAATGGCCCGGGAGGCCATTTTACTCACCATCA
CTGATATGATTGAATCAGGGCGCTATTCTTTAGCGCAAATTAAAGATCTTGGTCCGTTGGTTTATCAGAAAACCCATACT
GAATTTGATGGACAACAATGGTTTGTGATTGAGGTTGATTTGTCGGAGCTGGAAGGAAAACCACAGCGGATTAATATTTC
GCTACCGGATGTGTTAATTCGTCGAATTGATTCACGTGTTAAAACTCAGGATGATTACCGCGACCGTAGCCATTTTCTGG
CCGTTGCGGCAAAAAATGAATTATTAAGGATGGAAGGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References