Detailed information of TA system TA105177

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 599177..599704
• Replicon: chromosome
• Accession: NZ_CP029185
• Organism: Limnobaculum parvum strain HYN0051

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HYN51_RS02095
• Protein ID: WP_108901324.1
• Coordinates: 599177..599443 (-)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HYN51_RS02100
• Protein ID: WP_108901325.1
• Coordinates: 599447..599704 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HYN51_RS02065	595054..595935	-	882	WP_108901319.1	U32 family peptidase	-
HYN51_RS02070	595948..596943	-	996	WP_108901320.1	U32 family peptidase	-
HYN51_RS02075	597254..597775	+	522	WP_108901321.1	SCP2 domain-containing protein	-
HYN51_RS02080	597769..598272	+	504	WP_108901322.1	N-acetyltransferase	-
HYN51_RS02085	598269..598616	-	348	WP_108901323.1	GIY-YIG nuclease family protein	-
HYN51_RS02090	598727..599176	+	450	WP_108902126.1	YhbP family protein	-
HYN51_RS02095	599177..599443	-	267	WP_108901324.1	type II toxin-antitoxin system YafQ family toxin	Toxin
HYN51_RS02100	599447..599704	-	258	WP_108901325.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
HYN51_RS02105	599914..600378	-	465	WP_108901326.1	anaerobic ribonucleoside-triphosphate reductase-activating protein	-
HYN51_RS02110	600509..602668	-	2160	WP_108901327.1	anaerobic ribonucleoside-triphosphate reductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (1-88)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-85)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10154.67 Da
• Isoelectric Point: 9.8732

>T105177 WP_108901324.1 NZ_CP029185:c599443-599177 [Limnobaculum parvum]
MLTIVYQNRFKKDAKHYVNNRNAQRIILNTIAMLQTGQPLPAGYREHKLSGSYVGYLECHGSPDILLIYQRTDSELRLYR
VGSHSALF

Nucleotide

• Length: 267 bp

>T105177 NZ_CP029185:c599443-599177 [Limnobaculum parvum]
ATGCTAACGATTGTTTATCAGAATCGATTTAAAAAAGACGCTAAACACTATGTAAATAATAGAAATGCGCAAAGGATCAT
CCTGAATACAATCGCCATGCTACAAACAGGCCAACCGCTACCAGCTGGCTACCGGGAGCATAAGTTATCCGGTAGCTATG
TTGGCTATCTAGAATGTCATGGATCTCCAGACATTCTATTGATTTATCAACGTACTGATTCAGAATTGAGACTATATCGG
GTTGGCAGCCATTCCGCGCTGTTTTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9164.72 Da
• Isoelectric Point: 9.9512

>AT105177 WP_108901325.1 NZ_CP029185:c599704-599447 [Limnobaculum parvum]
MNDTIVKARVSPEIKAAAMANAKTLGLDLSTVIRLVVRQLAATGKIPEGLISPNKETLQAIKEFELGIGVHRANSVDELK
KDLGW

Nucleotide

• Length: 258 bp

>AT105177 NZ_CP029185:c599704-599447 [Limnobaculum parvum]
ATGAATGATACAATCGTAAAAGCGCGAGTTTCACCAGAAATAAAGGCGGCAGCAATGGCAAATGCAAAAACACTGGGGTT
AGATTTATCTACCGTCATCCGACTGGTAGTCAGACAGTTAGCGGCAACGGGAAAAATACCAGAAGGTTTAATTAGCCCCA
ATAAAGAAACTCTTCAGGCAATTAAAGAGTTTGAACTGGGTATTGGAGTACACCGTGCTAACTCGGTAGATGAACTGAAA
AAAGATCTGGGATGGTGA