Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc-RelB
Location 237271..237905 Replicon chromosome
Accession NZ_CP029185
Organism Limnobaculum parvum strain HYN0051

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag HYN51_RS00575 Protein ID WP_108901072.1
Coordinates 237271..237687 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag HYN51_RS00580 Protein ID WP_108901073.1
Coordinates 237684..237905 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYN51_RS00540 232483..233277 + 795 WP_108902108.1 outer membrane protein assembly factor BamE -
HYN51_RS00545 233283..234152 + 870 WP_157952942.1 hypothetical protein -
HYN51_RS00550 234488..234865 + 378 WP_108901067.1 BON domain-containing protein -
HYN51_RS00555 234963..235124 + 162 WP_157952943.1 DUF1328 domain-containing protein -
HYN51_RS00560 235595..235759 + 165 WP_157952944.1 hypothetical protein -
HYN51_RS00565 235862..236248 - 387 WP_108901070.1 hypothetical protein -
HYN51_RS00570 236433..237029 + 597 WP_108901071.1 hypothetical protein -
HYN51_RS00575 237271..237687 - 417 WP_108901072.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
HYN51_RS00580 237684..237905 - 222 WP_108901073.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HYN51_RS00585 238103..238345 + 243 WP_108901074.1 transposase -
HYN51_RS00590 238543..239406 - 864 WP_108901075.1 YicC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(5-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-52)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15756.81 Da        Isoelectric Point: 7.5196

>T105176 WP_108901072.1 NZ_CP029185:c237687-237271 [Limnobaculum parvum]
MIWVSAQEVIAFHDRILQRLPGVTGLSDPGRAEALIYRVQNRTHHEGVTDVFELAATYWVAIARGHIFNDDNKRTAFFVT
MAFLYRNGIKIRDNDNTLENLTVEAATGEKTTDQLAQHLRERVTILSQHVRHSRTPCT

Download         Length: 417 bp

>T105176 NZ_CP029185:c237687-237271 [Limnobaculum parvum]
ATGATATGGGTCAGCGCACAGGAAGTCATCGCTTTCCACGATCGCATATTGCAGCGGCTTCCCGGCGTTACAGGTCTATC
CGATCCCGGCAGAGCCGAAGCACTCATCTACCGGGTGCAAAACCGTACGCATCATGAAGGCGTTACCGATGTGTTTGAAC
TGGCCGCCACTTACTGGGTAGCTATTGCTCGTGGCCATATCTTTAATGATGACAATAAACGCACCGCATTTTTCGTTACT
ATGGCCTTTCTTTACCGCAACGGCATCAAGATCCGTGATAACGACAATACGCTGGAAAACTTAACGGTAGAGGCTGCGAC
AGGTGAGAAGACCACTGACCAATTAGCACAACATTTACGGGAGCGAGTGACAATTTTATCCCAACACGTTAGGCACTCTC
GTACTCCGTGTACTTAA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8077.91 Da        Isoelectric Point: 5.5675

>AT105176 WP_108901073.1 NZ_CP029185:c237905-237684 [Limnobaculum parvum]
MRTYTSTQARANISEVLDAATHGEPVEITRRDGSSAVVISKAEFEAYQNAKLDAEFDAIMQRHGHTVEALTNR

Download         Length: 222 bp

>AT105176 NZ_CP029185:c237905-237684 [Limnobaculum parvum]
ATGCGTACATACACCTCAACCCAAGCCCGCGCTAATATCTCAGAAGTGCTGGATGCGGCCACTCATGGTGAACCGGTTGA
AATCACTCGCAGAGACGGCAGCTCCGCCGTCGTTATCAGCAAGGCTGAATTCGAGGCATACCAAAATGCTAAGTTGGATG
CGGAGTTTGATGCGATTATGCAGCGTCATGGGCATACGGTAGAGGCGCTGACCAACCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References