Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3553170..3553757 Replicon chromosome
Accession NZ_CP029151
Organism Dokdonia sp. Dokd-P16

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag DCS32_RS15685 Protein ID WP_108879149.1
Coordinates 3553170..3553469 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DCS32_RS15690 Protein ID WP_108879150.1
Coordinates 3553473..3553757 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCS32_RS15670 3548280..3548669 + 390 WP_162533678.1 hypothetical protein -
DCS32_RS15675 3548843..3550864 + 2022 WP_108879147.1 tetratricopeptide repeat protein -
DCS32_RS15680 3551100..3552725 + 1626 WP_162533679.1 hypothetical protein -
DCS32_RS15685 3553170..3553469 + 300 WP_108879149.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DCS32_RS15690 3553473..3553757 + 285 WP_108879150.1 putative addiction module antidote protein Antitoxin
DCS32_RS15695 3553917..3554537 - 621 WP_108879151.1 SMI1/KNR4 family protein -
DCS32_RS15700 3554800..3555843 + 1044 WP_108879152.1 hypothetical protein -
DCS32_RS15705 3556134..3558734 - 2601 WP_108879153.1 T9SS type A sorting domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-91)

Antitoxin

Uncharacterized protein HI1420

(3-89)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11659.71 Da        Isoelectric Point: 10.6067

>T105056 WP_108879149.1 NZ_CP029151:3553170-3553469 [Dokdonia sp. Dokd-P16]
MFFIEKTSEFDKWLRKLKDFKAKAKIIFRVQKLETNEHFGDCKPVGDGIREMRINFSKGYRVYFKEKDGKVIVLLIGGDK
STQQNDIAKAKSIWKKLNK

Download         Length: 300 bp

>T105056 NZ_CP029151:3553170-3553469 [Dokdonia sp. Dokd-P16]
ATGTTCTTTATTGAAAAAACATCTGAATTTGACAAGTGGCTGAGAAAGCTAAAAGATTTTAAGGCTAAGGCTAAAATTAT
ATTCAGAGTTCAAAAATTAGAAACTAATGAACATTTTGGTGACTGTAAACCAGTTGGCGATGGAATTCGAGAAATGCGGA
TTAATTTTTCGAAGGGTTATCGTGTTTATTTCAAAGAAAAAGATGGAAAAGTAATAGTGCTTTTAATTGGCGGAGATAAA
TCTACTCAACAAAATGACATTGCGAAGGCGAAAAGTATTTGGAAAAAATTAAATAAATAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10101.69 Da        Isoelectric Point: 4.7513

>AT105056 WP_108879150.1 NZ_CP029151:3553473-3553757 [Dokdonia sp. Dokd-P16]
MGTSKFEIADYLESKEMIAEYLNTVLEEGDNADIINAIGHIAKAIGMTKIAEETGLSRPSLYKALSDGAKPQFATIMKVL
KAIGGQIQVNPMSV

Download         Length: 285 bp

>AT105056 NZ_CP029151:3553473-3553757 [Dokdonia sp. Dokd-P16]
ATGGGAACTTCAAAATTTGAAATAGCTGACTATTTGGAAAGCAAAGAAATGATTGCGGAATATCTAAATACGGTTTTAGA
AGAAGGAGACAATGCAGATATAATAAATGCAATTGGGCACATAGCAAAAGCAATCGGAATGACAAAAATTGCGGAAGAAA
CTGGTTTGAGCAGACCGAGTTTGTATAAAGCACTATCTGATGGAGCTAAGCCTCAATTTGCGACAATTATGAAAGTATTA
AAAGCAATCGGAGGACAAATTCAAGTGAACCCGATGTCAGTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References