Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3644482..3644627 Replicon chromosome
Accession NZ_CP029137
Organism Klebsiella pneumoniae strain AR376

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3644489..3644591 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3644482..3644627 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC13_RS19810 3640013..3641446 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CSC13_RS19815 3641562..3641801 + 240 WP_002911393.1 YebV family protein -
CSC13_RS19820 3641899..3642090 + 192 WP_002911395.1 YebW family protein -
CSC13_RS19825 3642087..3642740 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
CSC13_RS19830 3642897..3643865 + 969 WP_004151446.1 VirK/YbjX family protein -
CSC13_RS29555 3643970..3644113 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3644482..3644627 + 146 - - Antitoxin
- 3644489..3644591 - 103 - - Toxin
CSC13_RS19840 3644750..3645088 - 339 WP_002911404.1 YebY family protein -
CSC13_RS19845 3645105..3645974 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
CSC13_RS19850 3645978..3646352 - 375 WP_004151448.1 CopC domain-containing protein YobA -
CSC13_RS19855 3646465..3646695 + 231 WP_002911406.1 DNA polymerase III subunit theta -
CSC13_RS19860 3646774..3647433 + 660 WP_020324964.1 exodeoxyribonuclease X -
CSC13_RS19865 3647437..3649497 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T105036 NZ_CP029137:c3644591-3644489 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT105036 NZ_CP029137:3644482-3644627 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References