Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | yeeUV (cbtA-cbeA)/CbtA-CbeA |
| Location | 2397252..2398006 | Replicon | chromosome |
| Accession | NZ_CP029126 | ||
| Organism | Enterobacter hormaechei strain AR432 | ||
Toxin (Protein)
| Gene name | yeeV | Uniprot ID | A0A6L5EGB6 |
| Locus tag | CSC19_RS11855 | Protein ID | WP_032669201.1 |
| Coordinates | 2397252..2397629 (-) | Length | 126 a.a. |
Antitoxin (Protein)
| Gene name | yeeU | Uniprot ID | - |
| Locus tag | CSC19_RS11860 | Protein ID | WP_074143921.1 |
| Coordinates | 2397680..2398006 (-) | Length | 109 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CSC19_RS11825 | 2392865..2394709 | + | 1845 | WP_015571912.1 | RNA polymerase sigma factor RpoD | - |
| CSC19_RS11830 | 2394810..2395316 | - | 507 | WP_017384024.1 | G/U mismatch-specific DNA glycosylase | - |
| CSC19_RS11840 | 2395619..2396467 | - | 849 | WP_032669204.1 | DUF4942 domain-containing protein | - |
| CSC19_RS11845 | 2396531..2396734 | - | 204 | WP_032669203.1 | DUF957 domain-containing protein | - |
| CSC19_RS11850 | 2396764..2397255 | - | 492 | WP_032672023.1 | hypothetical protein | - |
| CSC19_RS11855 | 2397252..2397629 | - | 378 | WP_032669201.1 | TA system toxin CbtA family protein | Toxin |
| CSC19_RS11860 | 2397680..2398006 | - | 327 | WP_074143921.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin |
| CSC19_RS11865 | 2398063..2398284 | - | 222 | WP_023567997.1 | DUF987 domain-containing protein | - |
| CSC19_RS11870 | 2398305..2398784 | - | 480 | WP_032669200.1 | DNA repair protein RadC | - |
| CSC19_RS11875 | 2398796..2399239 | - | 444 | WP_032669199.1 | antirestriction protein | - |
| CSC19_RS11880 | 2399270..2400091 | - | 822 | WP_032669198.1 | DUF945 domain-containing protein | - |
| CSC19_RS11885 | 2400190..2400421 | - | 232 | Protein_2275 | DUF905 domain-containing protein | - |
| CSC19_RS11890 | 2400493..2400942 | - | 450 | WP_032669197.1 | hypothetical protein | - |
| CSC19_RS11895 | 2400939..2401394 | - | 456 | WP_000754598.1 | hypothetical protein | - |
| CSC19_RS11900 | 2401433..2402068 | - | 636 | WP_020837117.1 | hypothetical protein | - |
| CSC19_RS11905 | 2402065..2402778 | - | 714 | WP_032669194.1 | WYL domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 126 a.a. Molecular weight: 14157.93 Da Isoelectric Point: 6.2236
>T104999 WP_032669201.1 NZ_CP029126:c2397629-2397252 [Enterobacter hormaechei]
MQTQPLSSTQEATPRPSPVEIWQRLLSHLLDRHYGLTLNDTPFGNDGVIQEHIDAGISLCDAVNFIVEKYDLVRTDRRGF
NAETQSPLLSSIDILRARKATGLMTRNDYRTVTDITTGKYREVQP
MQTQPLSSTQEATPRPSPVEIWQRLLSHLLDRHYGLTLNDTPFGNDGVIQEHIDAGISLCDAVNFIVEKYDLVRTDRRGF
NAETQSPLLSSIDILRARKATGLMTRNDYRTVTDITTGKYREVQP
Download Length: 378 bp
>T104999 NZ_CP029126:c2397629-2397252 [Enterobacter hormaechei]
ATGCAAACCCAACCACTATCCTCAACTCAGGAGGCTACACCACGCCCGTCACCGGTGGAGATCTGGCAACGGCTTCTGAG
CCACCTGTTGGATCGTCACTACGGTCTGACACTCAACGACACTCCGTTCGGCAACGATGGCGTGATTCAGGAGCATATCG
ACGCCGGTATCTCACTGTGCGACGCGGTGAATTTTATCGTGGAGAAATACGATCTGGTACGAACCGACCGTCGCGGTTTT
AACGCAGAAACACAGTCGCCTCTTCTCAGCAGTATCGATATTCTCCGCGCCCGCAAAGCCACCGGACTGATGACCCGAAA
CGATTACAGAACGGTGACCGACATCACCACCGGTAAATACCGGGAGGTGCAGCCATGA
ATGCAAACCCAACCACTATCCTCAACTCAGGAGGCTACACCACGCCCGTCACCGGTGGAGATCTGGCAACGGCTTCTGAG
CCACCTGTTGGATCGTCACTACGGTCTGACACTCAACGACACTCCGTTCGGCAACGATGGCGTGATTCAGGAGCATATCG
ACGCCGGTATCTCACTGTGCGACGCGGTGAATTTTATCGTGGAGAAATACGATCTGGTACGAACCGACCGTCGCGGTTTT
AACGCAGAAACACAGTCGCCTCTTCTCAGCAGTATCGATATTCTCCGCGCCCGCAAAGCCACCGGACTGATGACCCGAAA
CGATTACAGAACGGTGACCGACATCACCACCGGTAAATACCGGGAGGTGCAGCCATGA
Antitoxin
Download Length: 109 a.a. Molecular weight: 11953.71 Da Isoelectric Point: 6.8397
>AT104999 WP_074143921.1 NZ_CP029126:c2398006-2397680 [Enterobacter hormaechei]
ITEPWWGLKRSITPCFGARLVQAGNRLHYLADRANITGQFSDADLRYLDQAFPLLLKQLELMLTSGELNPCHQHCVTLYA
KGLTCEADSLGSHGYVYLAIYPTPAATA
ITEPWWGLKRSITPCFGARLVQAGNRLHYLADRANITGQFSDADLRYLDQAFPLLLKQLELMLTSGELNPCHQHCVTLYA
KGLTCEADSLGSHGYVYLAIYPTPAATA
Download Length: 327 bp
>AT104999 NZ_CP029126:c2398006-2397680 [Enterobacter hormaechei]
ATCACTGAACCCTGGTGGGGGCTTAAACGCAGTATCACGCCCTGTTTTGGCGCACGGCTGGTACAGGCGGGCAACCGTCT
GCATTATCTCGCTGACCGGGCCAACATCACCGGACAGTTCAGCGACGCTGATTTACGGTATCTCGACCAGGCATTTCCAC
TGCTGCTCAAACAGCTTGAACTGATGCTCACCAGCGGTGAACTCAATCCCTGCCATCAGCACTGTGTCACGCTCTATGCA
AAAGGGCTGACCTGCGAGGCCGACTCCCTCGGCTCGCATGGTTACGTATACCTGGCGATTTATCCGACACCAGCGGCAAC
CGCATAA
ATCACTGAACCCTGGTGGGGGCTTAAACGCAGTATCACGCCCTGTTTTGGCGCACGGCTGGTACAGGCGGGCAACCGTCT
GCATTATCTCGCTGACCGGGCCAACATCACCGGACAGTTCAGCGACGCTGATTTACGGTATCTCGACCAGGCATTTCCAC
TGCTGCTCAAACAGCTTGAACTGATGCTCACCAGCGGTGAACTCAATCCCTGCCATCAGCACTGTGTCACGCTCTATGCA
AAAGGGCTGACCTGCGAGGCCGACTCCCTCGGCTCGCATGGTTACGTATACCTGGCGATTTATCCGACACCAGCGGCAAC
CGCATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|