Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2289407..2289678 Replicon chromosome
Accession NZ_CP029122
Organism Escherichia coli strain AR434

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2289537..2289640 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2289407..2289678 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC21_RS11635 2285962..2286624 - 663 WP_000944256.1 exodeoxyribonuclease X -
CSC21_RS11640 2286648..2287304 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CSC21_RS11645 2287406..2287636 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CSC21_RS11650 2287775..2288149 + 375 WP_000204699.1 CopC domain-containing protein YobA -
CSC21_RS11655 2288153..2289025 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
CSC21_RS11660 2289038..2289379 + 342 WP_000976492.1 YebY family protein -
- 2289407..2289678 - 272 - - Antitoxin
- 2289537..2289640 + 104 - - Toxin
CSC21_RS11665 2289775..2290431 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
CSC21_RS11670 2290432..2290623 - 192 WP_001296140.1 YebW family protein -
CSC21_RS11675 2290728..2290964 - 237 WP_001295499.1 DUF1480 family protein -
CSC21_RS11680 2291082..2292521 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T104974 NZ_CP029122:2289537-2289640 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT104974 NZ_CP029122:c2289678-2289407 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References