Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1994018..1994163 | Replicon | chromosome |
| Accession | NZ_CP029099 | ||
| Organism | Klebsiella pneumoniae strain AR438 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1994054..1994156 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1994018..1994163 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CSC25_RS10210 | 1989148..1991208 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| CSC25_RS10215 | 1991212..1991871 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| CSC25_RS10220 | 1991950..1992180 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| CSC25_RS10225 | 1992293..1992667 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| CSC25_RS10230 | 1992671..1993540 | + | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| CSC25_RS10235 | 1993557..1993895 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1994018..1994163 | - | 146 | - | - | Antitoxin |
| - | 1994054..1994156 | + | 103 | - | - | Toxin |
| CSC25_RS30410 | 1994531..1994674 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| CSC25_RS10245 | 1994779..1995747 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| CSC25_RS10250 | 1995904..1996557 | + | 654 | WP_002911396.1 | protein-serine/threonine phosphatase | - |
| CSC25_RS10255 | 1996554..1996745 | - | 192 | WP_002911395.1 | YebW family protein | - |
| CSC25_RS10260 | 1996843..1997082 | - | 240 | WP_002911393.1 | YebV family protein | - |
| CSC25_RS10265 | 1997198..1998631 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T104857 NZ_CP029099:1994054-1994156 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT104857 NZ_CP029099:c1994163-1994018 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
