Detailed information of TA system TA104842

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vagCD/VapC-VagC
• Location: 39114..39784
• Replicon: plasmid unnamed2
• Accession: NZ_CP029092
• Organism: Pseudomonas aeruginosa strain AR441

Toxin (Protein)

• Gene name: vagD
• Uniprot ID: -
• Locus tag: CSC28_RS01285
• Protein ID: WP_105446699.1
• Coordinates: 39114..39551 (-)
• Length: 146 a.a.

Antitoxin (Protein)

• Gene name: vagC
• Uniprot ID: -
• Locus tag: CSC28_RS01290
• Protein ID: WP_105446700.1
• Coordinates: 39548..39784 (-)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CSC28_RS01245	34247..34591	-	345	WP_105446694.1	hypothetical protein	-
CSC28_RS01250	34652..35155	-	504	WP_105446695.1	hypothetical protein	-
CSC28_RS01255	35172..35600	-	429	WP_105446696.1	hypothetical protein	-
CSC28_RS01260	35656..36492	-	837	WP_015272400.1	DUF945 domain-containing protein	-
CSC28_RS01265	37173..37433	-	261	WP_058565745.1	hypothetical protein	-
CSC28_RS01270	37445..37753	-	309	WP_058565746.1	hypothetical protein	-
CSC28_RS01275	37743..38555	-	813	WP_105446697.1	3'-5' exonuclease	-
CSC28_RS01280	38571..39107	-	537	WP_105446698.1	hypothetical protein	-
CSC28_RS01285	39114..39551	-	438	WP_105446699.1	type II toxin-antitoxin system VapC family toxin	Toxin
CSC28_RS01290	39548..39784	-	237	WP_105446700.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
CSC28_RS01295	39794..40219	-	426	WP_105446701.1	DUF192 domain-containing protein	-
CSC28_RS01300	40554..40859	-	306	WP_204100709.1	hypothetical protein	-
CSC28_RS01305	40887..41537	-	651	WP_058565752.1	DNA-binding protein	-
CSC28_RS01310	42129..43283	-	1155	WP_105446702.1	replication initiator protein A	-
CSC28_RS01315	43270..43887	-	618	WP_105446703.1	recombinase family protein	-
CSC28_RS35535	43902..44243	-	342	WP_123809515.1	hypothetical protein	-
CSC28_RS01320	44412..44672	-	261	WP_105446704.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..57052	57052

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 146 a.a.
• Molecular weight: 21505.80 Da
• Isoelectric Point: 5.5500

>T104842 WP_105446699.1 NZ_CP029092:c39551-39114 [Pseudomonas aeruginosa]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 438 bp

>T104842 NZ_CP029092:c39551-39114 [Pseudomonas aeruginosa]
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Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 11644.97 Da
• Isoelectric Point: 5.5500

>AT104842 WP_105446700.1 NZ_CP029092:c39784-39548 [Pseudomonas aeruginosa]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 237 bp

>AT104842 NZ_CP029092:c39784-39548 [Pseudomonas aeruginosa]
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