Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1(toxin)
Location 2769656..2770287 Replicon chromosome
Accession NZ_CP029049
Organism Miniimonas sp. S16

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DCS86_RS11900 Protein ID WP_159096537.1
Coordinates 2769916..2770287 (+) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DCS86_RS11895 Protein ID WP_108719168.1
Coordinates 2769656..2769913 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCS86_RS11870 2765198..2765524 + 327 WP_108719164.1 helix-turn-helix domain-containing protein -
DCS86_RS11875 2765721..2765975 + 255 WP_108719165.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
DCS86_RS11880 2765972..2766355 + 384 WP_159096536.1 type II toxin-antitoxin system VapC family toxin -
DCS86_RS11885 2766412..2768337 - 1926 WP_108719167.1 hypothetical protein -
DCS86_RS11890 2768641..2769618 + 978 WP_108720194.1 acyl-CoA desaturase -
DCS86_RS11895 2769656..2769913 + 258 WP_108719168.1 ribbon-helix-helix protein, CopG family Antitoxin
DCS86_RS11900 2769916..2770287 + 372 WP_159096537.1 type II toxin-antitoxin system VapC family toxin Toxin
DCS86_RS11905 2770309..2770806 - 498 WP_108719170.1 YajQ family cyclic di-GMP-binding protein -
DCS86_RS11915 2771120..2772172 - 1053 WP_108719171.1 EamA family transporter RarD -
DCS86_RS11930 2772529..2772699 + 171 WP_108719172.1 50S ribosomal protein L33 -
DCS86_RS11935 2772705..2773160 + 456 WP_108719173.1 MaoC family dehydratase N-terminal domain-containing protein -
DCS86_RS11940 2773157..2773618 + 462 WP_108719174.1 acyl dehydratase -
DCS86_RS11945 2773686..2774825 - 1140 WP_108719175.1 substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-109)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-39)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 12994.94 Da        Isoelectric Point: 6.2245

>T104640 WP_159096537.1 NZ_CP029049:2769916-2770287 [Miniimonas sp. S16]
VLVDTSVLIDVLRGEAAAAAVLRDARVAGPLHASEVTRLEVLAGMRAGEEGATRALLGVLTWHALNEQVAETAGELGRRW
LPGNRGIDSADLAIAATAMVLNARVLTRNVKHFPMFDGLSAPY

Download         Length: 372 bp

>T104640 NZ_CP029049:2769916-2770287 [Miniimonas sp. S16]
GTGCTCGTCGACACATCCGTGCTCATCGACGTGCTGCGGGGAGAGGCCGCCGCCGCGGCCGTGCTGCGGGACGCCCGGGT
GGCGGGCCCGCTTCACGCGAGCGAGGTGACGCGGCTCGAGGTGCTTGCGGGCATGCGAGCGGGGGAGGAGGGGGCCACCC
GAGCCCTTCTCGGTGTCCTCACCTGGCACGCGCTGAACGAGCAGGTCGCCGAGACCGCTGGCGAGCTCGGTCGACGATGG
CTTCCGGGCAACCGCGGCATCGACTCCGCTGATCTCGCGATAGCTGCCACCGCCATGGTGCTGAACGCCAGGGTGCTGAC
TCGGAACGTGAAGCACTTTCCGATGTTCGACGGCCTGTCCGCGCCCTACTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9389.45 Da        Isoelectric Point: 4.6722

>AT104640 WP_108719168.1 NZ_CP029049:2769656-2769913 [Miniimonas sp. S16]
MLRTQISLTAEDRRILDEEAARTGRSVSALIREAVTLAYAGKRDIQEDVRAIDDAVGAWKDRDVDGESYVEALRSGGRLR
DLGAQ

Download         Length: 258 bp

>AT104640 NZ_CP029049:2769656-2769913 [Miniimonas sp. S16]
ATGCTGCGCACCCAGATCTCGCTCACCGCAGAGGACCGGCGCATCCTCGACGAAGAGGCCGCACGGACCGGTCGATCCGT
CTCCGCGTTGATTCGCGAGGCCGTGACGCTGGCATACGCCGGAAAGCGGGACATCCAGGAGGACGTCCGAGCGATTGACG
ACGCGGTCGGTGCGTGGAAGGACCGCGACGTCGACGGTGAGTCCTACGTCGAGGCGCTCCGCTCGGGTGGTCGTCTCCGC
GACCTCGGCGCACAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References