Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-PHD
Location 2181403..2182072 Replicon chromosome
Accession NZ_CP029049
Organism Miniimonas sp. S16

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DCS86_RS09510 Protein ID WP_108718796.1
Coordinates 2181674..2182072 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DCS86_RS09505 Protein ID WP_108718795.1
Coordinates 2181403..2181669 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCS86_RS09485 2177221..2178432 + 1212 WP_108720118.1 Nramp family divalent metal transporter -
DCS86_RS16640 2178544..2179143 - 600 WP_159096480.1 MarR family transcriptional regulator -
DCS86_RS09495 2179993..2180685 + 693 WP_108718793.1 YggS family pyridoxal phosphate-dependent enzyme -
DCS86_RS09500 2180783..2181337 - 555 WP_108718794.1 dienelactone hydrolase -
DCS86_RS09505 2181403..2181669 + 267 WP_108718795.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DCS86_RS09510 2181674..2182072 + 399 WP_108718796.1 type II toxin-antitoxin system VapC family toxin Toxin
DCS86_RS09515 2182162..2182698 + 537 WP_108718797.1 acyl-CoA thioesterase -
DCS86_RS09520 2182889..2184022 + 1134 WP_108718798.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-122)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-42)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 13903.86 Da        Isoelectric Point: 4.4237

>T104639 WP_108718796.1 NZ_CP029049:2181674-2182072 [Miniimonas sp. S16]
VPRPGLLDTSVFIAREDGRPLDVDALPAESAVSVVTIAELQVGVLSAPDTEVRARRMATLATASQVTPLPITVEAARAWA
TLRVRLAEEGRRANVNDLWIAAIALAEGLDVVTHDSDYDVIASVGGPGIVRV

Download         Length: 399 bp

>T104639 NZ_CP029049:2181674-2182072 [Miniimonas sp. S16]
GTGCCGAGGCCCGGTCTCCTCGACACCAGCGTCTTCATCGCCCGCGAGGACGGTCGACCTCTCGACGTCGATGCTCTCCC
GGCCGAGTCCGCTGTCAGCGTGGTGACGATCGCGGAGCTCCAGGTCGGCGTGCTCTCGGCGCCGGACACCGAGGTGCGTG
CCCGGCGGATGGCGACGCTCGCGACAGCGTCCCAGGTCACCCCGCTGCCGATCACGGTCGAGGCCGCCCGCGCGTGGGCG
ACGCTGCGGGTCCGGTTGGCGGAGGAAGGTCGCCGAGCGAACGTCAACGATCTGTGGATCGCCGCGATCGCTCTCGCGGA
GGGACTCGACGTCGTGACGCACGACTCGGACTACGACGTCATCGCCTCCGTCGGGGGTCCCGGAATCGTCCGGGTCTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9257.20 Da        Isoelectric Point: 6.0587

>AT104639 WP_108718795.1 NZ_CP029049:2181403-2181669 [Miniimonas sp. S16]
MSTATARDLRNHTADILRRVTSGGSVTITVHGAAVAELHPVSSSRPTFFSRADLVEGLGATQADSALRETLRHLAGDGTD
DLDDSLAR

Download         Length: 267 bp

>AT104639 NZ_CP029049:2181403-2181669 [Miniimonas sp. S16]
ATGTCCACGGCCACGGCTCGAGACCTGCGCAACCACACGGCGGACATCCTTCGACGCGTGACATCGGGCGGGTCGGTCAC
CATCACGGTGCACGGCGCCGCAGTGGCCGAGCTCCATCCCGTGAGTTCCTCTCGTCCCACGTTCTTCAGCCGAGCCGACC
TGGTCGAGGGCCTGGGCGCCACCCAGGCCGACTCTGCCCTCCGGGAGACCCTCCGGCACTTGGCCGGCGACGGCACCGAC
GATCTCGACGACTCCCTTGCCCGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References