Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1917031..1917644 Replicon chromosome
Accession NZ_CP029049
Organism Miniimonas sp. S16

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag DCS86_RS08265 Protein ID WP_108720087.1
Coordinates 1917031..1917399 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag DCS86_RS08270 Protein ID WP_108718605.1
Coordinates 1917426..1917644 (-) Length 73 a.a.

Genomic Context

DCS86_RS08230DCS86_RS08255DCS86_RS08260DCS86_RS08275DCS86_RS08280DCS86_RS08235DCS86_RS08240DCS86_RS08245DCS86_RS08250DCS86_RS08265DCS86_RS08270
Location: 1912201..1912629 (429 bp)
Type: Others
Protein ID: WP_159096454.1
Location: 1916155..1916505 (351 bp)
Type: Others
Protein ID: Protein_1609
Location: 1916626..1916952 (327 bp)
Type: Others
Protein ID: WP_108720086.1
Location: 1918268..1921276 (3009 bp)
Type: Others
Protein ID: WP_199916585.1
Location: 1921351..1921788 (438 bp)
Type: Others
Protein ID: WP_108718606.1
Location: 1913201..1913887 (687 bp)
Type: Others
Protein ID: WP_159096455.1
Location: 1914033..1914878 (846 bp)
Type: Others
Protein ID: WP_108718603.1
Location: 1914868..1915404 (537 bp)
Type: Others
Protein ID: WP_108718604.1
Location: 1915471..1916007 (537 bp)
Type: Others
Protein ID: WP_108720085.1
Location: 1917031..1917399 (369 bp)
Type: Toxin
Protein ID: WP_108720087.1
Location: 1917426..1917644 (219 bp)
Type: Antitoxin
Protein ID: WP_108718605.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DCS86_RS082301912201..1912629+429WP_159096454.1hypothetical protein-
DCS86_RS082351913201..1913887-687WP_159096455.1hypothetical protein-
DCS86_RS082401914033..1914878-846WP_108718603.1hypothetical protein-
DCS86_RS082451914868..1915404-537WP_108718604.1RNA polymerase sigma factor-
DCS86_RS082501915471..1916007-537WP_108720085.1ADP-ribosylglycohydrolase family protein-
DCS86_RS082551916155..1916505+351Protein_1609DUF488 family protein-
DCS86_RS082601916626..1916952+327WP_108720086.1LuxR family transcriptional regulator-
DCS86_RS082651917031..1917399-369WP_108720087.1type II toxin-antitoxin system PemK/MazF family toxinToxin
DCS86_RS082701917426..1917644-219WP_108718605.1ribbon-helix-helix domain-containing proteinAntitoxin
DCS86_RS082751918268..1921276+3009WP_199916585.1DEAD/DEAH box helicase-
DCS86_RS082801921351..1921788+438WP_108718606.1PPOX class F420-dependent oxidoreductase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(5-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13145.01 Da        Isoelectric Point: 11.4347

>T104638 WP_108720087.1 NZ_CP029049:c1917399-1917031 [Miniimonas sp. S16]
VTHPPRRAEIWWVDLAPAVGSEADSRRPAVVVSNDGANSAAASLGRGVVTVVPLTTTLTRVLPFQVVIPASEEVGHGLRQ
DSKAQAEQVRSVDVRRLVSRAGRLRPDTMARLEDALRLHLGL

Download         Length: 369 bp

>T104638 NZ_CP029049:c1917399-1917031 [Miniimonas sp. S16]
GTGACGCACCCTCCGCGGCGCGCAGAGATCTGGTGGGTCGACCTGGCTCCTGCTGTGGGCAGTGAGGCGGACAGTCGAAG
ACCCGCGGTCGTCGTGAGCAACGACGGCGCCAACTCGGCCGCCGCCTCGCTCGGCCGAGGCGTGGTGACGGTGGTCCCGC
TCACCACGACGCTGACGCGCGTGCTGCCCTTCCAGGTCGTCATCCCGGCGAGTGAGGAGGTGGGTCACGGCCTTCGCCAG
GACTCCAAGGCTCAGGCGGAGCAGGTGCGGTCCGTCGACGTGCGGCGCCTCGTCTCGCGGGCCGGACGCCTACGCCCCGA
CACGATGGCGCGGCTGGAGGACGCGCTGCGTCTGCACCTCGGCTTGTAG

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 7513.35 Da        Isoelectric Point: 4.1087

>AT104638 WP_108718605.1 NZ_CP029049:c1917644-1917426 [Miniimonas sp. S16]
MKLSVSLPIADVEFLDAFTRGHGLASRSAAVAQAVRALRAESLTSAYEQAFDDGVEEAAAWDVAVADGMSQA

Download         Length: 219 bp

>AT104638 NZ_CP029049:c1917644-1917426 [Miniimonas sp. S16]
ATGAAACTGAGTGTGAGCCTTCCGATCGCGGACGTCGAGTTTCTCGACGCGTTCACACGCGGGCACGGTCTAGCGTCGCG
CTCGGCCGCGGTCGCGCAGGCAGTCCGAGCACTGCGCGCGGAGTCGCTGACCAGCGCGTACGAGCAGGCGTTCGACGACG
GCGTCGAGGAGGCCGCGGCGTGGGACGTCGCCGTCGCCGACGGCATGAGTCAGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References