Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1917031..1917644 Replicon chromosome
Accession NZ_CP029049
Organism Miniimonas sp. S16

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag DCS86_RS08265 Protein ID WP_108720087.1
Coordinates 1917031..1917399 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag DCS86_RS08270 Protein ID WP_108718605.1
Coordinates 1917426..1917644 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCS86_RS08230 1912201..1912629 + 429 WP_159096454.1 hypothetical protein -
DCS86_RS08235 1913201..1913887 - 687 WP_159096455.1 hypothetical protein -
DCS86_RS08240 1914033..1914878 - 846 WP_108718603.1 hypothetical protein -
DCS86_RS08245 1914868..1915404 - 537 WP_108718604.1 RNA polymerase sigma factor -
DCS86_RS08250 1915471..1916007 - 537 WP_108720085.1 ADP-ribosylglycohydrolase family protein -
DCS86_RS08255 1916155..1916505 + 351 Protein_1609 DUF488 family protein -
DCS86_RS08260 1916626..1916952 + 327 WP_108720086.1 LuxR family transcriptional regulator -
DCS86_RS08265 1917031..1917399 - 369 WP_108720087.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
DCS86_RS08270 1917426..1917644 - 219 WP_108718605.1 ribbon-helix-helix domain-containing protein Antitoxin
DCS86_RS08275 1918268..1921276 + 3009 WP_199916585.1 DEAD/DEAH box helicase -
DCS86_RS08280 1921351..1921788 + 438 WP_108718606.1 PPOX class F420-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(5-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13145.01 Da        Isoelectric Point: 11.4347

>T104638 WP_108720087.1 NZ_CP029049:c1917399-1917031 [Miniimonas sp. S16]
VTHPPRRAEIWWVDLAPAVGSEADSRRPAVVVSNDGANSAAASLGRGVVTVVPLTTTLTRVLPFQVVIPASEEVGHGLRQ
DSKAQAEQVRSVDVRRLVSRAGRLRPDTMARLEDALRLHLGL

Download         Length: 369 bp

>T104638 NZ_CP029049:c1917399-1917031 [Miniimonas sp. S16]
GTGACGCACCCTCCGCGGCGCGCAGAGATCTGGTGGGTCGACCTGGCTCCTGCTGTGGGCAGTGAGGCGGACAGTCGAAG
ACCCGCGGTCGTCGTGAGCAACGACGGCGCCAACTCGGCCGCCGCCTCGCTCGGCCGAGGCGTGGTGACGGTGGTCCCGC
TCACCACGACGCTGACGCGCGTGCTGCCCTTCCAGGTCGTCATCCCGGCGAGTGAGGAGGTGGGTCACGGCCTTCGCCAG
GACTCCAAGGCTCAGGCGGAGCAGGTGCGGTCCGTCGACGTGCGGCGCCTCGTCTCGCGGGCCGGACGCCTACGCCCCGA
CACGATGGCGCGGCTGGAGGACGCGCTGCGTCTGCACCTCGGCTTGTAG

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 7513.35 Da        Isoelectric Point: 4.1087

>AT104638 WP_108718605.1 NZ_CP029049:c1917644-1917426 [Miniimonas sp. S16]
MKLSVSLPIADVEFLDAFTRGHGLASRSAAVAQAVRALRAESLTSAYEQAFDDGVEEAAAWDVAVADGMSQA

Download         Length: 219 bp

>AT104638 NZ_CP029049:c1917644-1917426 [Miniimonas sp. S16]
ATGAAACTGAGTGTGAGCCTTCCGATCGCGGACGTCGAGTTTCTCGACGCGTTCACACGCGGGCACGGTCTAGCGTCGCG
CTCGGCCGCGGTCGCGCAGGCAGTCCGAGCACTGCGCGCGGAGTCGCTGACCAGCGCGTACGAGCAGGCGTTCGACGACG
GCGTCGAGGAGGCCGCGGCGTGGGACGTCGCCGTCGCCGACGGCATGAGTCAGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References