Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 1037081..1037587 Replicon chromosome
Accession NZ_CP029049
Organism Miniimonas sp. S16

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag DCS86_RS04555 Protein ID WP_108718009.1
Coordinates 1037081..1037335 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DCS86_RS04560 Protein ID WP_108718010.1
Coordinates 1037336..1037587 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCS86_RS04535 1032434..1033639 + 1206 WP_108718005.1 pyridoxal phosphate-dependent aminotransferase -
DCS86_RS04540 1033757..1035208 + 1452 WP_108718006.1 DUF2029 domain-containing protein -
DCS86_RS04545 1035257..1036090 - 834 WP_108718007.1 hypothetical protein -
DCS86_RS04550 1036327..1037025 + 699 WP_108718008.1 DUF3500 domain-containing protein -
DCS86_RS04555 1037081..1037335 - 255 WP_108718009.1 Txe/YoeB family addiction module toxin Toxin
DCS86_RS04560 1037336..1037587 - 252 WP_108718010.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DCS86_RS04565 1037664..1038335 - 672 WP_108719984.1 mismatch-specific DNA-glycosylase -
DCS86_RS04575 1038539..1039183 - 645 WP_108718011.1 TetR/AcrR family transcriptional regulator -
DCS86_RS04580 1039248..1040552 + 1305 WP_108718012.1 glycosyltransferase -
DCS86_RS04590 1040828..1041655 - 828 WP_108718013.1 ornithine carbamoyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(3-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-69)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9985.33 Da        Isoelectric Point: 8.0350

>T104637 WP_108718009.1 NZ_CP029049:c1037335-1037081 [Miniimonas sp. S16]
VRLVWDRSAWEDYTYWQAADRRVLKRINTLIEACLREPAHGIGKPEQLKYGAQGAWSRRITDEHRLVYLVDGDDLVILQA
RYHY

Download         Length: 255 bp

>T104637 NZ_CP029049:c1037335-1037081 [Miniimonas sp. S16]
GTGCGACTCGTCTGGGACCGCTCGGCCTGGGAGGACTACACGTACTGGCAGGCGGCCGACCGACGGGTCCTCAAGCGGAT
CAACACGCTGATCGAGGCGTGCCTGCGCGAGCCGGCCCACGGCATCGGCAAACCCGAGCAGCTCAAGTACGGCGCCCAAG
GCGCCTGGTCCCGGCGGATCACAGACGAGCACAGGCTCGTGTACCTCGTCGACGGGGACGACCTGGTGATCCTCCAGGCG
CGCTACCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9491.51 Da        Isoelectric Point: 4.6652

>AT104637 WP_108718010.1 NZ_CP029049:c1037587-1037336 [Miniimonas sp. S16]
MSISASEARKTLFPLIERVNDDREAIEIVSRRGNAVLMAADDYAAWQETAYLFRSPANARRLLDAFERAREHQTEAHELD
QAD

Download         Length: 252 bp

>AT104637 NZ_CP029049:c1037587-1037336 [Miniimonas sp. S16]
ATGTCCATCAGTGCGAGCGAGGCGCGCAAGACCCTCTTCCCGCTCATCGAGAGGGTGAACGACGACCGCGAGGCGATCGA
GATCGTCTCGCGGCGCGGCAACGCCGTCCTCATGGCGGCCGACGACTACGCCGCGTGGCAGGAGACGGCCTACCTGTTCC
GATCGCCCGCGAATGCGCGCCGGCTTCTGGACGCGTTCGAGCGTGCCCGCGAGCACCAGACAGAGGCGCACGAGCTCGAC
CAGGCGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References