Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1(toxin)
Location 865522..866156 Replicon chromosome
Accession NZ_CP029049
Organism Miniimonas sp. S16

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DCS86_RS03830 Protein ID WP_108719963.1
Coordinates 865522..865902 (-) Length 127 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DCS86_RS03835 Protein ID WP_108717888.1
Coordinates 865899..866156 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCS86_RS16525 861674..863272 + 1599 WP_159096365.1 hypothetical protein -
DCS86_RS03815 863277..863684 + 408 WP_108717886.1 hypothetical protein -
DCS86_RS03820 863928..864644 - 717 WP_108719962.1 alpha/beta hydrolase -
DCS86_RS03825 864738..865490 - 753 WP_108717887.1 alpha/beta hydrolase -
DCS86_RS03830 865522..865902 - 381 WP_108719963.1 type II toxin-antitoxin system VapC family toxin Toxin
DCS86_RS03835 865899..866156 - 258 WP_108717888.1 ribbon-helix-helix protein, CopG family Antitoxin
DCS86_RS03840 866176..867852 - 1677 WP_108717889.1 ATP-binding cassette domain-containing protein -
DCS86_RS03845 868218..871148 + 2931 WP_159096366.1 rhamnogalacturonan lyase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-111)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-39)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 13343.28 Da        Isoelectric Point: 6.0723

>T104636 WP_108719963.1 NZ_CP029049:c865902-865522 [Miniimonas sp. S16]
VILVDSDVLIAHLRGVASARDWLRDAPAETLTVSAVTVAEVTGGMRESEERAVTALLGVLPTVPVTDPVARRAGALRRAF
DRSHSGIALGDYLIAATALEHGFQLATLNTRHFSMFPGLEPPFAVG

Download         Length: 381 bp

>T104636 NZ_CP029049:c865902-865522 [Miniimonas sp. S16]
GTGATCCTGGTCGACTCCGACGTCCTCATCGCCCACCTGCGGGGCGTCGCGAGCGCCCGCGACTGGTTGCGCGACGCGCC
GGCGGAGACGCTGACGGTCAGCGCGGTGACCGTGGCCGAGGTGACGGGTGGGATGCGGGAGTCGGAGGAGCGCGCCGTCA
CCGCACTGCTCGGGGTGCTCCCGACCGTTCCGGTCACCGATCCGGTCGCGCGGCGAGCCGGCGCGTTGCGTCGCGCGTTC
GACCGCAGCCACTCGGGCATCGCGCTGGGGGACTACCTCATCGCGGCCACGGCCCTCGAGCACGGCTTCCAGCTGGCTAC
GCTCAACACGCGCCACTTCTCGATGTTCCCCGGCCTCGAGCCGCCGTTCGCCGTCGGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9343.46 Da        Isoelectric Point: 5.1599

>AT104636 WP_108717888.1 NZ_CP029049:c866156-865899 [Miniimonas sp. S16]
MQRTNIFLEERQTDSLDAMARLEGVSRAEVIRRIIDRAIDGEGNAEARRRAAIDLSFGAAARIAVERGADDARAAQLASM
WGRDA

Download         Length: 258 bp

>AT104636 NZ_CP029049:c866156-865899 [Miniimonas sp. S16]
ATGCAGCGCACCAACATCTTCCTCGAGGAGCGACAGACGGACTCGCTGGACGCGATGGCGCGCCTCGAGGGTGTCTCGCG
CGCCGAGGTGATCCGCCGGATCATCGACCGCGCGATCGACGGCGAGGGGAACGCCGAGGCGCGTCGACGCGCCGCGATCG
ACCTCTCCTTCGGTGCCGCCGCCCGGATCGCCGTGGAGCGGGGCGCCGACGACGCGCGCGCGGCCCAGCTCGCGAGCATG
TGGGGTCGGGACGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References