Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 774676..774821 Replicon chromosome
Accession NZ_CP028990
Organism Klebsiella pneumoniae strain AR_0142

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 774712..774814 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 774676..774821 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM389_RS03695 769806..771866 + 2061 WP_004151449.1 oligopeptidase B -
AM389_RS03700 771870..772529 - 660 WP_002911407.1 exodeoxyribonuclease X -
AM389_RS03705 772608..772838 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AM389_RS03710 772951..773325 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AM389_RS03715 773329..774198 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
AM389_RS03720 774215..774553 + 339 WP_016529031.1 YebY family protein -
- 774676..774821 - 146 - - Antitoxin
- 774712..774814 + 103 - - Toxin
AM389_RS28065 775190..775333 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AM389_RS03730 775438..776406 - 969 WP_004151446.1 VirK/YbjX family protein -
AM389_RS03735 776563..777216 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
AM389_RS03740 777213..777404 - 192 WP_002911395.1 YebW family protein -
AM389_RS03745 777502..777741 - 240 WP_002911393.1 YebV family protein -
AM389_RS03750 777857..779290 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T104538 NZ_CP028990:774712-774814 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT104538 NZ_CP028990:c774821-774676 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References