Detailed information of TA system TA104534

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 4389451..4390310
• Replicon: chromosome
• Accession: NZ_CP028968
• Organism: Aminobacter sp. MSH1

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: DCS14_RS22145
• Protein ID: WP_100079112.1
• Coordinates: 4389451..4389981 (-)
• Length: 177 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: DCS14_RS22150
• Protein ID: WP_100079340.1
• Coordinates: 4389969..4390310 (-)
• Length: 114 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DCS14_RS22125	4385614..4385844	+	231	WP_100079116.1	hypothetical protein	-
DCS14_RS22130	4385914..4386342	-	429	WP_100079115.1	hypothetical protein	-
DCS14_RS22135	4386733..4388844	+	2112	WP_100079114.1	ParB/RepB/Spo0J family partition protein	-
DCS14_RS22140	4389026..4389442	+	417	WP_100079113.1	hypothetical protein	-
DCS14_RS22145	4389451..4389981	-	531	WP_100079112.1	GNAT family N-acetyltransferase	Toxin
DCS14_RS22150	4389969..4390310	-	342	WP_100079340.1	DUF1778 domain-containing protein	Antitoxin
DCS14_RS22155	4391108..4391425	+	318	WP_100079111.1	DUF736 domain-containing protein	-
DCS14_RS22160	4391799..4392644	+	846	WP_100079110.1	DUF945 domain-containing protein	-
DCS14_RS22165	4392954..4393169	+	216	WP_100079109.1	hypothetical protein	-
DCS14_RS22170	4393258..4393737	+	480	WP_100079108.1	DUF2285 domain-containing protein	-
DCS14_RS22175	4393748..4394035	-	288	WP_100079339.1	DUF2285 domain-containing protein	-
DCS14_RS22180	4394507..4394776	+	270	WP_100079107.1	helix-turn-helix domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (49-151)

Antitoxin

• Vibrio phage ICP1, Orf50 (32-107)

Sequences

Toxin

Protein

• Length: 177 a.a.
• Molecular weight: 19136.80 Da
• Isoelectric Point: 4.8890

>T104534 WP_100079112.1 NZ_CP028968:c4389981-4389451 [Aminobacter sp. MSH1]
MAEIDEAADDPELPLSPPVPLAAEHDLSEFDCGEPVLNDWLRHRALKNESRFSRTYVVCEGNRVVGYFCISAGSVERGAA
PGKVRRNAPDVIPVSIIGRLAVSLDHARKGLGADLLSDALRRIALASQSIGIGAVMVQAKDDAARRFYLRCAEFIEYPED
SRTLFLPIETVVAGFG

Nucleotide

• Length: 531 bp

>T104534 NZ_CP028968:c4389981-4389451 [Aminobacter sp. MSH1]
ATGGCAGAAATAGACGAAGCGGCGGACGATCCCGAATTGCCGCTATCGCCTCCTGTTCCCCTGGCTGCTGAACACGATCT
TTCCGAGTTCGACTGCGGCGAGCCGGTGCTGAATGACTGGCTGCGTCATCGGGCCTTGAAGAACGAAAGCCGGTTCTCGC
GCACATACGTCGTGTGCGAGGGCAATCGGGTCGTCGGCTATTTCTGCATTTCAGCGGGATCGGTCGAACGGGGAGCGGCT
CCCGGTAAGGTGAGGCGCAACGCCCCGGACGTGATTCCGGTTTCGATCATCGGTCGGCTGGCTGTCAGTCTTGACCATGC
GCGCAAGGGTCTCGGCGCGGACCTGCTTTCGGACGCATTGCGCCGGATCGCGCTGGCCTCGCAAAGCATCGGCATTGGGG
CTGTGATGGTCCAGGCCAAGGACGATGCCGCCAGACGCTTCTATCTGCGCTGCGCGGAGTTCATCGAATATCCCGAGGAC
AGCCGGACGCTGTTCCTGCCTATCGAAACGGTGGTCGCGGGCTTCGGCTAG

Antitoxin

Protein

• Length: 114 a.a.
• Molecular weight: 12465.26 Da
• Isoelectric Point: 10.7798

>AT104534 WP_100079340.1 NZ_CP028968:c4390310-4389969 [Aminobacter sp. MSH1]
MAKTRLAPSESTRSASPAVAARASTSEAKGSINLRIETDTRQLIDDAAAVLGKTRTEFMVESARRQAVDVLLDQRLFTLD
PERYDAFMRALDNPPAPGPKLKALLRRTPAWQK

Nucleotide

• Length: 342 bp

>AT104534 NZ_CP028968:c4390310-4389969 [Aminobacter sp. MSH1]
ATGGCAAAAACTCGTCTCGCCCCTTCCGAATCTACCCGCTCCGCGTCTCCTGCCGTCGCGGCCCGCGCATCTACGTCCGA
GGCCAAGGGCAGCATCAACTTGCGGATCGAGACCGACACCCGCCAGCTCATCGACGATGCGGCGGCGGTCCTCGGCAAGA
CGCGCACCGAGTTCATGGTGGAGAGCGCGAGGCGACAGGCGGTCGATGTGCTGCTCGACCAGCGCCTGTTCACACTCGAT
CCGGAACGCTACGACGCCTTCATGCGGGCGCTCGACAATCCGCCTGCACCGGGGCCTAAGCTCAAGGCTCTGCTACGCCG
GACCCCGGCATGGCAGAAATAG