Detailed information of TA system TA104532

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2027071..2027590
• Replicon: chromosome
• Accession: NZ_CP028968
• Organism: Aminobacter sp. MSH1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: DCS14_RS10615
• Protein ID: WP_108606985.1
• Coordinates: 2027309..2027590 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: DCS14_RS10610
• Protein ID: WP_108606984.1
• Coordinates: 2027071..2027319 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DCS14_RS10595	2022215..2023174	-	960	WP_108606981.1	ABC transporter permease	-
DCS14_RS10600	2023191..2024774	-	1584	WP_108606982.1	ABC transporter substrate-binding protein	-
DCS14_RS10605	2024917..2026923	-	2007	WP_108606983.1	CocE/NonD family hydrolase	-
DCS14_RS10610	2027071..2027319	+	249	WP_108606984.1	plasmid stabilization protein	Antitoxin
DCS14_RS10615	2027309..2027590	+	282	WP_108606985.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
DCS14_RS10620	2027598..2028191	-	594	WP_108606986.1	nucleoside deaminase	-
DCS14_RS10625	2028196..2028696	-	501	WP_108609738.1	ureidoglycolate lyase	-
DCS14_RS10630	2028718..2029563	-	846	WP_108606987.1	(S)-ureidoglycine aminohydrolase	-
DCS14_RS10635	2029569..2031002	-	1434	WP_108606988.1	allantoinase PuuE	-
DCS14_RS10640	2031181..2031546	+	366	WP_108606989.1	hydroxyisourate hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 11044.89 Da
• Isoelectric Point: 10.6209

>T104532 WP_108606985.1 NZ_CP028968:2027309-2027590 [Aminobacter sp. MSH1]
MRYEVEFLETALKEWKALDANTREHFRKKLKERCENPRVPSAKLHGAKDRYKIKLRSAGYRLVYEVEDGRLVVLVIAIGR
RDRLEVYAKAARR

Nucleotide

• Length: 282 bp

>T104532 NZ_CP028968:2027309-2027590 [Aminobacter sp. MSH1]
ATGCGCTATGAGGTCGAGTTCCTCGAAACCGCACTGAAGGAATGGAAAGCGCTCGACGCCAATACACGCGAGCACTTCCG
CAAGAAGCTGAAGGAGCGCTGTGAAAACCCGCGCGTCCCCTCGGCCAAGCTGCATGGCGCCAAGGACCGCTACAAGATCA
AGCTGCGAAGTGCCGGCTATCGCCTTGTCTACGAGGTGGAGGATGGCAGGCTGGTGGTGCTGGTCATCGCCATAGGCCGG
CGCGACCGCCTCGAGGTTTATGCCAAGGCGGCGAGGCGCTGA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 8933.31 Da
• Isoelectric Point: 4.5702

>AT104532 WP_108606984.1 NZ_CP028968:2027071-2027319 [Aminobacter sp. MSH1]
MPNTVLAEVTASVSELKRNPMGTVAAGEGFPVAILNRNEPAFYCVPAKAFEAMMDRLEDIELNAIADARKGEKRIRVDLD
AL

Nucleotide

• Length: 249 bp

>AT104532 NZ_CP028968:2027071-2027319 [Aminobacter sp. MSH1]
ATGCCGAACACAGTTCTTGCCGAAGTTACTGCCAGCGTCTCGGAGCTGAAAAGGAACCCGATGGGCACGGTGGCTGCCGG
GGAAGGGTTTCCGGTCGCCATTCTCAATCGCAACGAACCGGCCTTCTACTGCGTGCCTGCCAAGGCCTTCGAGGCGATGA
TGGACCGGCTGGAGGACATCGAGCTCAACGCGATTGCCGACGCGCGCAAGGGCGAAAAGCGTATCCGGGTCGACCTGGAT
GCGCTATGA