Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 891358..891999 Replicon chromosome
Accession NZ_CP028962
Organism Burkholderia sp. IDO3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DCN14_RS04155 Protein ID WP_096505594.1
Coordinates 891661..891999 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag DCN14_RS04150 Protein ID WP_096505596.1
Coordinates 891358..891657 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCN14_RS04125 886528..887799 + 1272 WP_096505602.1 Rieske 2Fe-2S domain-containing protein -
DCN14_RS04130 887813..888301 + 489 WP_059601577.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
DCN14_RS04135 888318..888644 + 327 WP_044847551.1 non-heme iron oxygenase ferredoxin subunit -
DCN14_RS04140 888634..889854 + 1221 WP_096505600.1 FAD-dependent oxidoreductase -
DCN14_RS04145 890023..891309 + 1287 WP_096505598.1 DUF445 domain-containing protein -
DCN14_RS04150 891358..891657 - 300 WP_096505596.1 putative addiction module antidote protein Antitoxin
DCN14_RS04155 891661..891999 - 339 WP_096505594.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DCN14_RS04165 892361..894001 + 1641 WP_096505592.1 acetolactate synthase large subunit -
DCN14_RS04170 894030..895463 + 1434 WP_096505590.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(16-109)

Antitoxin

Uncharacterized protein HI1420

(4-96)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12562.52 Da        Isoelectric Point: 9.9828

>T104517 WP_096505594.1 NZ_CP028962:c891999-891661 [Burkholderia sp. IDO3]
MVDILRSMPYSAPTFSIRTTDVFDAWFAGLPDRVARRRIQAPIDRLSMGNPGDWKSAGSPIVEMRIDHGPGYRVYYVRRG
TIWVILLCGGAKSTQQADIRAAHAMLARLDLE

Download         Length: 339 bp

>T104517 NZ_CP028962:c891999-891661 [Burkholderia sp. IDO3]
ATGGTTGACATACTGCGATCCATGCCCTACAGTGCCCCAACATTCAGCATCCGGACCACCGACGTCTTCGACGCGTGGTT
CGCCGGCCTGCCCGACCGTGTCGCCAGGCGCCGCATCCAGGCGCCCATCGACCGCCTGTCGATGGGCAATCCCGGCGACT
GGAAATCCGCCGGCTCGCCCATCGTCGAAATGCGTATCGACCACGGGCCCGGCTATCGCGTCTACTACGTGCGGCGCGGA
ACGATATGGGTGATCCTGCTCTGCGGCGGCGCCAAGTCGACGCAACAGGCGGATATCCGCGCCGCGCACGCGATGCTCGC
GCGGCTCGACCTGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10732.19 Da        Isoelectric Point: 6.9777

>AT104517 WP_096505596.1 NZ_CP028962:c891657-891358 [Burkholderia sp. IDO3]
MDKIKTRPWDSAEHLKTDDDMAEYFDACLREAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGTKAHA

Download         Length: 300 bp

>AT104517 NZ_CP028962:c891657-891358 [Burkholderia sp. IDO3]
ATGGACAAGATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTGAAAACCGACGACGACATGGCCGAATACTTCGATGC
CTGTCTGCGGGAAGCCGGCGACGACCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCCCGTGCCCGCGGCATGTCGC
AGGTCGCGCGCGACGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACG
ATCCTGAAGGTCATCAAGGCACTCGGCCTGCAACTGCACGGCACCAAGGCGCACGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References