Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 921356..921872 Replicon chromosome
Accession NZ_CP028950
Organism Enterobacter cloacae complex sp. FDA-CDC-AR_0164

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AM410_RS04500 Protein ID WP_108647580.1
Coordinates 921356..921640 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AM410_RS04505 Protein ID WP_108647582.1
Coordinates 921630..921872 (-) Length 81 a.a.

Genomic Context

AM410_RS04480AM410_RS04490AM410_RS04495AM410_RS04500AM410_RS04505AM410_RS04510AM410_RS04515AM410_RS04520
Location: 917717..918289 (573 bp)
Type: Others
Protein ID: WP_108647578.1
Location: 918657..920795 (2139 bp)
Type: Others
Protein ID: WP_020885401.1
Location: 920888..921352 (465 bp)
Type: Others
Protein ID: WP_059306428.1
Location: 921356..921640 (285 bp)
Type: Toxin
Protein ID: WP_108647580.1
Location: 921630..921872 (243 bp)
Type: Antitoxin
Protein ID: WP_108647582.1
Location: 921950..923860 (1911 bp)
Type: Others
Protein ID: WP_014168384.1
Location: 923880..925016 (1137 bp)
Type: Others
Protein ID: WP_108647584.1
Location: 925135..925875 (741 bp)
Type: Others
Protein ID: WP_059306432.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AM410_RS04480917717..918289+573WP_108647578.1PTS sugar transporter subunit IIA-
AM410_RS04490918657..920795+2139WP_020885401.1anaerobic ribonucleoside-triphosphate reductase-
AM410_RS04495920888..921352+465WP_059306428.1anaerobic ribonucleoside-triphosphate reductase-activating protein-
AM410_RS04500921356..921640-285WP_108647580.1type II toxin-antitoxin system RelE/ParE family toxinToxin
AM410_RS04505921630..921872-243WP_108647582.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
AM410_RS04510921950..923860-1911WP_014168384.1BglG family transcription antiterminator-
AM410_RS04515923880..925016-1137WP_108647584.1lactonase family protein-
AM410_RS04520925135..925875-741WP_059306432.1KDGP aldolase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10952.75 Da        Isoelectric Point: 10.3193

>T104474 WP_108647580.1 NZ_CP028950:c921640-921356 [Enterobacter cloacae complex sp. FDA-CDC-AR_0164]
MSYELVFDPRAFKEWTRLGDTVKNQFKKKLANVLVNPRVESARLHGLPDCDKIKLRSQGYRLVYQVQDNVVTVCVIAIGK
REKSAFYHDVNKRL

Download         Length: 285 bp

>T104474 NZ_CP028950:c921640-921356 [Enterobacter cloacae complex sp. FDA-CDC-AR_0164]
ATGAGTTATGAACTCGTATTTGATCCGAGGGCGTTCAAGGAGTGGACCAGGCTGGGTGATACCGTAAAAAATCAGTTTAA
GAAGAAGCTTGCGAACGTGTTGGTGAACCCCAGGGTTGAATCGGCTCGCCTGCATGGCCTGCCTGATTGCGACAAGATAA
AACTCAGATCCCAGGGTTATCGTTTGGTCTATCAGGTTCAGGACAACGTTGTGACGGTATGTGTTATTGCTATCGGTAAG
AGAGAGAAATCAGCCTTTTATCATGACGTAAACAAACGGCTTTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9099.52 Da        Isoelectric Point: 5.1231

>AT104474 WP_108647582.1 NZ_CP028950:c921872-921630 [Enterobacter cloacae complex sp. FDA-CDC-AR_0164]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTVSDSEDELIQTVRERLANPQKGIKVRLDEL

Download         Length: 243 bp

>AT104474 NZ_CP028950:c921872-921630 [Enterobacter cloacae complex sp. FDA-CDC-AR_0164]
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAACGAGGCTTATGCCGTGCTTGAAAAACTCAATATCACGCC
AACGGAAGCCGTTCGGTTACTGTTTCAGTACGTTGCGGAGACGGGGCGTATGCCGGTGAAAACGGTCACTGTTAGCGACA
GTGAAGATGAACTCATACAGACAGTCCGGGAGCGGCTGGCTAATCCGCAAAAAGGAATTAAGGTTAGGCTGGATGAGTTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References