Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3609975..3610115 Replicon chromosome
Accession NZ_CP028946
Organism Serratia marcescens strain AR_0124

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3610019..3610115 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3609975..3610115 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM371_RS17145 3605175..3605600 + 426 WP_033638066.1 RNA polymerase-binding protein DksA -
AM371_RS17150 3605793..3606746 + 954 WP_033646426.1 prolyl aminopeptidase -
AM371_RS17155 3606778..3607008 - 231 WP_033642715.1 DNA polymerase III subunit theta -
AM371_RS17160 3607354..3607872 + 519 WP_025302449.1 non-heme ferritin -
AM371_RS17165 3608166..3608582 + 417 WP_046686875.1 CopC domain-containing protein YobA -
AM371_RS17170 3608585..3609466 + 882 WP_033646425.1 copper homeostasis membrane protein CopD -
AM371_RS17175 3609536..3609877 + 342 WP_025302452.1 YebY family protein -
- 3609975..3610115 - 141 - - Antitoxin
- 3610019..3610115 + 97 - - Toxin
AM371_RS17180 3610368..3610772 + 405 WP_033646424.1 hypothetical protein -
AM371_RS17185 3610769..3610987 - 219 WP_033638114.1 hypothetical protein -
AM371_RS24740 3611051..3611215 - 165 WP_154067227.1 hypothetical protein -
AM371_RS17190 3611507..3611857 + 351 WP_033638116.1 DUF4377 domain-containing protein -
AM371_RS17195 3612041..3613240 + 1200 WP_033638117.1 trans-2-enoyl-CoA reductase family protein -
AM371_RS17200 3613468..3613686 + 219 WP_033646423.1 hypothetical protein -
AM371_RS17205 3613858..3614163 + 306 WP_033646422.1 hypothetical protein -
AM371_RS17210 3614207..3614542 + 336 WP_033638120.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T104423 NZ_CP028946:3610019-3610115 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT104423 NZ_CP028946:c3610115-3609975 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References