Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 683378..683986 Replicon chromosome
Accession NZ_CP028942
Organism Polynucleobacter sp. MWH-UH21B

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DCO17_RS03670 Protein ID WP_173955451.1
Coordinates 683690..683986 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DCO17_RS03665 Protein ID WP_173955450.1
Coordinates 683378..683689 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCO17_RS03645 679291..679974 - 684 WP_173955447.1 GntR family transcriptional regulator -
DCO17_RS03650 680153..681337 + 1185 WP_173955448.1 aminotransferase class V-fold PLP-dependent enzyme -
DCO17_RS03655 681482..681886 + 405 WP_173956692.1 heme-binding protein -
DCO17_RS03660 681893..683296 + 1404 WP_173955449.1 DEAD/DEAH box helicase -
DCO17_RS03665 683378..683689 - 312 WP_173955450.1 putative addiction module antidote protein Antitoxin
DCO17_RS03670 683690..683986 - 297 WP_173955451.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DCO17_RS03675 684017..684973 - 957 WP_173955452.1 tRNA glutamyl-Q(34) synthetase GluQRS -
DCO17_RS03680 684977..688591 + 3615 WP_173955453.1 DNA polymerase III subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-97)

Antitoxin

Uncharacterized protein HI1420

(15-99)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11370.14 Da        Isoelectric Point: 10.2207

>T104411 WP_173955451.1 NZ_CP028942:c683986-683690 [Polynucleobacter sp. MWH-UH21B]
MYRVFETDNFLEWLDNLKDLSTRIRLARRLDRARLGNLGDIKALSDGIYEMREKFGPGWRMYYVLRGKTIIVMLGGGDKS
SQSNDIKAAKRLAKQLED

Download         Length: 297 bp

>T104411 NZ_CP028942:c683986-683690 [Polynucleobacter sp. MWH-UH21B]
ATGTATAGAGTTTTTGAGACTGATAATTTCCTTGAGTGGCTGGATAACCTTAAAGATCTTTCAACTCGGATTCGACTGGC
TAGAAGACTGGATAGAGCTAGATTAGGAAACTTAGGAGATATTAAGGCTCTCAGTGATGGCATTTATGAAATGCGTGAAA
AGTTTGGCCCTGGATGGCGAATGTATTACGTATTAAGAGGTAAAACGATTATTGTGATGCTAGGCGGTGGAGACAAGTCA
AGTCAATCTAATGATATTAAAGCCGCAAAAAGGTTAGCGAAGCAATTGGAGGATTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11251.23 Da        Isoelectric Point: 10.7661

>AT104411 WP_173955450.1 NZ_CP028942:c683689-683378 [Polynucleobacter sp. MWH-UH21B]
MKATKVSKKIKISDLTEFDITRHLKSKRAMTEYLNQVIADGDDAELAAALGHIARAKGMAEISKSSGITREALYKALKPN
TKPRFNTVSKVIGALGMRIIVHA

Download         Length: 312 bp

>AT104411 NZ_CP028942:c683689-683378 [Polynucleobacter sp. MWH-UH21B]
ATGAAAGCTACTAAAGTAAGCAAGAAAATAAAAATTAGTGATTTAACTGAATTTGATATTACTCGACATCTCAAAAGTAA
ACGTGCGATGACCGAGTATTTAAATCAAGTGATTGCTGATGGCGATGATGCTGAATTAGCAGCCGCCTTAGGACATATTG
CTAGAGCGAAAGGTATGGCGGAAATATCTAAATCAAGCGGAATTACAAGAGAAGCTTTATACAAAGCCCTTAAGCCGAAC
ACCAAACCCCGTTTTAATACGGTATCGAAAGTTATTGGCGCCTTAGGCATGAGAATTATCGTCCATGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References