Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4972447..4972592 Replicon chromosome
Accession NZ_CP028932
Organism Klebsiella pneumoniae strain AR_0153

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4972483..4972585 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4972447..4972592 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM400_RS27410 4967577..4969637 + 2061 WP_004151449.1 oligopeptidase B -
AM400_RS27415 4969641..4970300 - 660 WP_043906809.1 exodeoxyribonuclease X -
AM400_RS27420 4970379..4970609 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AM400_RS27425 4970722..4971096 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AM400_RS27430 4971100..4971969 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
AM400_RS27435 4971986..4972324 + 339 WP_002911404.1 YebY family protein -
- 4972447..4972592 - 146 - - Antitoxin
- 4972483..4972585 + 103 - - Toxin
AM400_RS29470 4972961..4973104 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AM400_RS27445 4973209..4974177 - 969 WP_004151446.1 VirK/YbjX family protein -
AM400_RS27450 4974334..4974987 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
AM400_RS27455 4974984..4975175 - 192 WP_002911395.1 YebW family protein -
AM400_RS27460 4975273..4975512 - 240 WP_002911393.1 YebV family protein -
AM400_RS27465 4975628..4977061 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T104394 NZ_CP028932:4972483-4972585 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT104394 NZ_CP028932:c4972592-4972447 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References