Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3556559..3557149 Replicon chromosome
Accession NZ_CP028923
Organism Roseivirga pacifica strain 9dcg1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag DCC35_RS15705 Protein ID WP_137091704.1
Coordinates 3556559..3556864 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DCC35_RS15710 Protein ID WP_137091705.1
Coordinates 3556865..3557149 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCC35_RS15685 3551784..3552263 + 480 WP_137091701.1 hypothetical protein -
DCC35_RS15690 3552406..3552852 + 447 WP_137091702.1 hypothetical protein -
DCC35_RS15695 3553053..3553982 + 930 WP_137091703.1 hypothetical protein -
DCC35_RS15700 3554318..3555596 - 1279 Protein_3119 group II intron reverse transcriptase/maturase -
DCC35_RS15705 3556559..3556864 + 306 WP_137091704.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DCC35_RS15710 3556865..3557149 + 285 WP_137091705.1 putative addiction module antidote protein Antitoxin
DCC35_RS15715 3557241..3557918 + 678 WP_137091706.1 VOC family protein -
DCC35_RS15720 3558191..3559282 + 1092 WP_137091707.1 DDE-type integrase/transposase/recombinase -
DCC35_RS15725 3559506..3560531 + 1026 WP_137091708.1 hypothetical protein -
DCC35_RS15730 3560790..3561104 - 315 WP_175402840.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3543264..3559282 16018


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-97)

Antitoxin

Uncharacterized protein HI1420

(3-91)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 12012.94 Da        Isoelectric Point: 10.0391

>T104376 WP_137091704.1 NZ_CP028923:3556559-3556864 [Roseivirga pacifica]
MYIIEQTTEFEKWFRKLKDRKAKAKILLRLQRIEDQGNYGDCQPIGEGLSELRIHYAKGYRVYFKERGDTLVLLLIGGDK
STQSKDIKKAKELWEQYKNKI

Download         Length: 306 bp

>T104376 NZ_CP028923:3556559-3556864 [Roseivirga pacifica]
ATGTATATAATTGAACAAACCACTGAATTTGAAAAGTGGTTTCGAAAGTTAAAAGACAGAAAAGCAAAAGCTAAAATTTT
GCTCCGTCTACAGAGAATAGAGGATCAAGGTAATTATGGCGATTGCCAACCAATTGGCGAAGGTCTTTCCGAATTACGGA
TACATTATGCAAAAGGGTATCGGGTATATTTTAAAGAACGTGGAGATACACTTGTATTGCTATTAATTGGAGGAGATAAA
TCAACCCAAAGTAAAGACATTAAAAAAGCAAAAGAACTTTGGGAGCAGTATAAAAACAAGATTTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10471.99 Da        Isoelectric Point: 5.1052

>AT104376 WP_137091705.1 NZ_CP028923:3556865-3557149 [Roseivirga pacifica]
MKTTRFEIANYLEDDEMIQEYLNTVLEEGDSRDIVVALGHIAKAIGMSKIAEQTGLSRPSLYKALSENSKPQFDTILKVI
RAIGSNLKLNISTN

Download         Length: 285 bp

>AT104376 NZ_CP028923:3556865-3557149 [Roseivirga pacifica]
ATGAAAACTACAAGATTCGAAATTGCTAATTATCTTGAAGATGACGAGATGATTCAGGAGTATTTAAATACGGTTTTAGA
AGAGGGGGATTCAAGAGATATTGTTGTTGCTTTGGGTCACATCGCCAAAGCAATTGGGATGTCAAAAATCGCAGAACAAA
CTGGATTGAGTAGACCTAGTCTGTATAAAGCTCTATCAGAAAATTCAAAACCTCAATTTGATACTATTTTGAAGGTAATA
AGAGCTATTGGAAGTAATCTGAAATTAAATATTTCAACAAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References