Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA(toxin)
Location 600116..600696 Replicon chromosome
Accession NZ_CP028923
Organism Roseivirga pacifica strain 9dcg1

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag DCC35_RS02760 Protein ID WP_137089353.1
Coordinates 600116..600358 (+) Length 81 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag DCC35_RS02765 Protein ID WP_137089354.1
Coordinates 600355..600696 (+) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCC35_RS02750 596954..598264 - 1311 WP_137089351.1 peptidoglycan DD-metalloendopeptidase family protein -
DCC35_RS02755 599040..599708 + 669 WP_137089352.1 hypothetical protein -
DCC35_RS02760 600116..600358 + 243 WP_137089353.1 type II toxin-antitoxin system HicA family toxin Toxin
DCC35_RS02765 600355..600696 + 342 WP_137089354.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
DCC35_RS02770 600981..601208 + 228 WP_137092579.1 hypothetical protein -
DCC35_RS02775 601205..601441 + 237 WP_137089355.1 hypothetical protein -
DCC35_RS02780 601887..603029 - 1143 WP_137089356.1 type II secretion system F family protein -
DCC35_RS02785 603016..603507 - 492 WP_137089357.1 hypothetical protein -
DCC35_RS02790 603485..603775 - 291 WP_137089358.1 hypothetical protein -
DCC35_RS02795 603763..604866 - 1104 WP_137089359.1 hypothetical protein -
DCC35_RS02800 604856..605479 - 624 WP_137089360.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(20-80)

Antitoxin

Uncharacterised protein family HicB

(54-104)


Sequences

Toxin        


Download         Length: 81 a.a.        Molecular weight: 9415.28 Da        Isoelectric Point: 10.6297

>T104374 WP_137089353.1 NZ_CP028923:600116-600358 [Roseivirga pacifica]
MSKKEKLIRRFLTKPSDFHYKEMVILLSYFGFKEVKKGKTFGSRVKFENEEGIPIILHKPHPSGIMKKYQMSQIKEVLGL

Download         Length: 243 bp

>T104374 NZ_CP028923:600116-600358 [Roseivirga pacifica]
ATGTCTAAAAAGGAGAAACTGATTCGACGGTTTCTTACAAAACCATCAGATTTTCATTATAAGGAGATGGTGATCTTATT
AAGTTACTTTGGATTTAAAGAAGTTAAGAAAGGAAAAACATTTGGATCAAGAGTGAAATTTGAAAATGAAGAGGGTATTC
CAATTATTTTGCATAAACCTCACCCGAGCGGAATAATGAAAAAATACCAGATGAGCCAGATAAAGGAGGTATTAGGGTTA
TGA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12701.48 Da        Isoelectric Point: 5.9037

>AT104374 WP_137089354.1 NZ_CP028923:600355-600696 [Roseivirga pacifica]
MKYLNYKGYTGSIEYSPEDNLLFGKVLGIKGLISYEGETGKQLENDFKESIEEYFSDCKLKGISPERPFKGSFNVRISSS
LHQKAALMAIEMKTSLNNLVAEAIRQRVGEDPV

Download         Length: 342 bp

>AT104374 NZ_CP028923:600355-600696 [Roseivirga pacifica]
ATGAAATATTTAAATTATAAAGGATATACCGGAAGCATTGAATATAGTCCTGAAGACAATCTATTGTTTGGGAAAGTCCT
CGGCATAAAAGGCCTTATTTCTTATGAAGGTGAAACAGGAAAGCAATTAGAGAACGATTTTAAAGAATCAATTGAGGAAT
ATTTTTCCGATTGTAAGTTAAAAGGAATTTCTCCGGAACGGCCTTTCAAGGGAAGCTTTAATGTTCGTATATCTTCAAGT
CTTCACCAAAAAGCGGCATTAATGGCTATCGAAATGAAAACTTCATTAAATAACCTTGTAGCAGAGGCTATCCGGCAACG
AGTTGGGGAGGATCCTGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References