Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 3370687..3371213 Replicon chromosome
Accession NZ_CP028918
Organism Gemmobacter sp. HYN0069

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HYN69_RS16290 Protein ID WP_108436673.1
Coordinates 3370687..3370983 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HYN69_RS16295 Protein ID WP_108436674.1
Coordinates 3370980..3371213 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYN69_RS16250 3365728..3366036 + 309 WP_108436665.1 zf-TFIIB domain-containing protein -
HYN69_RS16255 3366082..3366522 - 441 WP_108436666.1 molybdenum cofactor biosynthesis protein MoaE -
HYN69_RS16260 3366524..3366772 - 249 WP_108436667.1 molybdopterin converting factor subunit 1 -
HYN69_RS16265 3366769..3367434 - 666 WP_108436668.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
HYN69_RS16270 3367556..3368458 + 903 WP_108436669.1 tRNA pseudouridine(55) synthase TruB -
HYN69_RS16275 3368546..3369058 + 513 WP_108436670.1 DUF1643 domain-containing protein -
HYN69_RS16280 3369050..3370099 - 1050 WP_159082506.1 hypothetical protein -
HYN69_RS16285 3370360..3370629 + 270 WP_108436672.1 30S ribosomal protein S15 -
HYN69_RS16290 3370687..3370983 - 297 WP_108436673.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HYN69_RS16295 3370980..3371213 - 234 WP_108436674.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HYN69_RS16300 3371426..3373564 + 2139 WP_108436675.1 polyribonucleotide nucleotidyltransferase -
HYN69_RS16305 3373632..3374366 - 735 WP_108436676.1 FkbM family methyltransferase -
HYN69_RS16310 3374363..3375208 - 846 WP_159082507.1 glycosyltransferase family 2 protein -
HYN69_RS16315 3375363..3376019 - 657 WP_108436678.1 peroxiredoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(6-76)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11234.91 Da        Isoelectric Point: 5.9691

>T104372 WP_108436673.1 NZ_CP028918:c3370983-3370687 [Gemmobacter sp. HYN0069]
VTRPVQLRPLAEADLAEIWDHTLAEWGSRQAEAYLAGLGKIFDLLAEHPEIARLRTEFVPPLRLHPYRAHLIIFQSGETL
EVIRVVHGRTDWLAFLTD

Download         Length: 297 bp

>T104372 NZ_CP028918:c3370983-3370687 [Gemmobacter sp. HYN0069]
GTGACGCGACCGGTTCAGCTACGCCCCTTGGCCGAAGCCGATCTGGCAGAAATCTGGGACCATACGCTTGCGGAATGGGG
ATCGCGTCAGGCCGAGGCCTATCTTGCGGGTCTGGGCAAAATATTCGACTTGCTGGCCGAGCATCCCGAGATCGCGCGGC
TTCGCACCGAATTCGTGCCGCCCTTGCGTCTGCACCCCTATCGCGCCCATCTGATCATCTTTCAAAGCGGCGAAACGCTC
GAGGTGATCCGCGTGGTCCATGGGCGGACCGATTGGCTGGCATTCCTGACCGACTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8617.84 Da        Isoelectric Point: 9.8265

>AT104372 WP_108436674.1 NZ_CP028918:c3371213-3370980 [Gemmobacter sp. HYN0069]
MATMNISLPEAMKAYAEAQARDGRFANVSDYMRDLIRRDQERAKARDEIQALAEQGMASGPPRPFDMAAFLAARRKA

Download         Length: 234 bp

>AT104372 NZ_CP028918:c3371213-3370980 [Gemmobacter sp. HYN0069]
ATGGCGACGATGAACATTTCCCTTCCCGAAGCGATGAAAGCCTATGCCGAGGCGCAGGCCCGCGACGGAAGATTTGCAAA
TGTCAGCGATTATATGCGCGACCTGATCCGCCGCGATCAGGAACGGGCAAAGGCGCGGGACGAGATTCAGGCATTGGCCG
AGCAGGGTATGGCAAGCGGGCCGCCGCGCCCGTTCGACATGGCCGCGTTTCTGGCGGCGCGGCGCAAGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References