Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 5242113..5243592 Replicon chromosome
Accession NZ_CP028908
Organism Bradyrhizobium sp. WD16

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag DB459_RS24235 Protein ID WP_253708983.1
Coordinates 5242113..5242982 (-) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag DB459_RS24240 Protein ID WP_253708985.1
Coordinates 5242975..5243592 (-) Length 206 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DB459_RS24215 (DB459_24170) 5238564..5239013 - 450 WP_253708972.1 hypothetical protein -
DB459_RS24220 (DB459_24175) 5239187..5240470 + 1284 WP_253707432.1 IS256 family transposase -
DB459_RS24225 (DB459_24180) 5240467..5240718 - 252 WP_253708975.1 hypothetical protein -
DB459_RS24230 (DB459_24185) 5240776..5242116 - 1341 WP_253708978.1 YiiX/YebB-like N1pC/P60 family cysteine hydrolase -
DB459_RS24235 (DB459_24190) 5242113..5242982 - 870 WP_253708983.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
DB459_RS24240 (DB459_24195) 5242975..5243592 - 618 WP_253708985.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
DB459_RS24245 (DB459_24200) 5243724..5243951 - 228 WP_253708988.1 DUF2274 domain-containing protein -
DB459_RS24250 (DB459_24205) 5243953..5245176 - 1224 WP_253708991.1 TrbI/VirB10 family protein -
DB459_RS24255 (DB459_24210) 5245173..5246216 - 1044 WP_253708993.1 P-type conjugative transfer protein TrbG -
DB459_RS24260 (DB459_24215) 5246213..5246896 - 684 WP_253708996.1 conjugal transfer protein TrbF -
DB459_RS24265 (DB459_24220) 5246896..5248221 - 1326 WP_253708999.1 P-type conjugative transfer protein TrbL -
DB459_RS24270 (DB459_24225) 5248224..5248493 - 270 WP_253709002.1 putative entry exclusion protein TrbK-alt -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 5189261..5320556 131295
- flank IS/Tn - - 5239187..5240470 1283


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-265)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(9-56)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32151.98 Da        Isoelectric Point: 5.8416

>T104364 WP_253708983.1 NZ_CP028908:c5242982-5242113 [Bradyrhizobium sp. WD16]
MAKELKNIGASVRTRLLQLAKASGQSFDLVLTRFALERLLFRLGQSSHADRFVLKGAMLMMSWFDDPHRGTRDLDLLGFG
NPEAEPMLATFREIMALEIADGVEFDIAALRVDRIREELEYGGLRLRTTASISGARVGLTIDIGFGDAMEPGLEVLDYPS
MLEFPAPRLRAYARETVIAEKFQAMIALGRANSRMKDFYDIWILSRSFTFDDDRLPRAIAATFARRGTPVPQDPPDALTT
AFAEDAQKQRQWRAFVGDVAHDPGDLGIVIRDLAAFLMPQAASAARLSK

Download         Length: 870 bp

>T104364 NZ_CP028908:c5242982-5242113 [Bradyrhizobium sp. WD16]
ATGGCTAAAGAGCTCAAGAATATCGGTGCCTCGGTGCGCACCCGCCTGCTGCAACTCGCCAAGGCGAGTGGACAGAGCTT
CGATCTCGTCCTGACGCGCTTCGCCCTCGAACGGCTACTCTTCAGGCTCGGTCAATCATCGCATGCCGACCGCTTCGTTC
TGAAAGGCGCGATGCTGATGATGAGCTGGTTTGACGACCCTCATCGTGGCACGCGCGATCTTGATCTGTTGGGTTTTGGA
AATCCCGAAGCCGAACCAATGCTGGCGACGTTCCGCGAAATCATGGCGCTGGAAATCGCCGATGGCGTGGAATTCGACAT
TGCGGCGCTGCGCGTCGATCGCATCCGTGAGGAGCTGGAATACGGGGGACTGCGGCTGCGAACAACGGCTTCGATAAGCG
GAGCCCGCGTCGGCCTGACCATCGACATCGGCTTTGGAGACGCAATGGAGCCAGGGCTCGAGGTATTGGACTATCCTTCT
ATGCTGGAGTTTCCCGCGCCCCGCCTGCGAGCCTATGCGCGCGAGACGGTGATCGCCGAGAAGTTCCAGGCGATGATAGC
GTTGGGGCGAGCAAACAGCCGGATGAAGGACTTCTACGACATCTGGATTCTCAGCCGGTCCTTCACCTTCGACGATGACA
GATTGCCACGAGCGATTGCCGCCACGTTCGCGCGACGTGGAACGCCAGTTCCTCAAGACCCACCCGATGCGTTGACAACG
GCCTTTGCCGAGGATGCGCAGAAGCAGCGACAGTGGCGGGCGTTCGTCGGCGACGTCGCTCATGATCCTGGTGATCTAGG
GATCGTCATCAGAGATTTGGCAGCGTTCCTTATGCCTCAAGCCGCTTCTGCAGCGAGATTGAGCAAATGA

Antitoxin


Download         Length: 206 a.a.        Molecular weight: 22376.93 Da        Isoelectric Point: 10.0951

>AT104364 WP_253708985.1 NZ_CP028908:c5243592-5242975 [Bradyrhizobium sp. WD16]
MPEPVSQRRIAQTVLKARGIARLAELRAEGVTAATMSRMERDGEVLRLARGLYQLPDAPLDVHHSLAEAAKRLPKGVVCL
VSALAFHGLTDQLPRHVWMAIGQKDWAPKADGVSIRLVRFTDRLLADGVETHTIEGVSVNVFGVAKTIADCFRYRNKIGL
SVAIEGLQEALRQRKATPDEIAKQAERGAVATVIRPYLEALTANG

Download         Length: 618 bp

>AT104364 NZ_CP028908:c5243592-5242975 [Bradyrhizobium sp. WD16]
TTGCCCGAACCCGTGTCCCAACGCCGAATTGCCCAGACCGTGCTGAAAGCGCGTGGCATCGCGCGCCTGGCGGAACTGCG
CGCAGAGGGAGTGACGGCTGCCACCATGAGCCGCATGGAGCGTGATGGCGAGGTGCTCCGGCTCGCGCGCGGGCTTTATC
AGCTCCCTGATGCCCCTCTCGACGTTCACCACAGTCTCGCAGAGGCCGCAAAACGCCTGCCAAAGGGGGTTGTCTGCCTC
GTCTCAGCGCTCGCGTTCCATGGCCTTACCGATCAACTGCCCAGGCATGTGTGGATGGCCATCGGCCAAAAGGATTGGGC
GCCCAAGGCTGACGGCGTGTCAATTCGGCTCGTACGATTCACGGATCGCCTGCTAGCGGATGGTGTCGAGACCCACACCA
TCGAGGGGGTGTCAGTGAATGTCTTCGGCGTCGCCAAGACGATCGCAGACTGCTTCCGATATCGGAACAAGATTGGCCTG
TCCGTCGCGATTGAAGGCCTCCAGGAAGCGCTGCGTCAGCGCAAGGCGACCCCAGACGAAATTGCCAAGCAGGCGGAGCG
TGGCGCGGTCGCGACAGTCATTCGCCCCTATCTCGAGGCACTGACCGCCAATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References