Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2388772..2389368 Replicon chromosome
Accession NZ_CP028901
Organism Algicoccus marinus strain HZ20

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DBV39_RS10900 Protein ID WP_108623229.1
Coordinates 2389069..2389368 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DBV39_RS10895 Protein ID WP_108621547.1
Coordinates 2388772..2389065 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DBV39_RS10875 2384494..2384643 - 150 Protein_2067 IS4 family transposase -
DBV39_RS10880 2384731..2385090 + 360 WP_108621545.1 nucleotidyltransferase domain-containing protein -
DBV39_RS10885 2384988..2385285 + 298 Protein_2069 DUF86 domain-containing protein -
DBV39_RS19515 2385602..2385817 - 216 WP_159078906.1 hypothetical protein -
DBV39_RS10890 2386192..2388069 - 1878 WP_159078907.1 diguanylate cyclase -
DBV39_RS10895 2388772..2389065 - 294 WP_108621547.1 putative addiction module antidote protein Antitoxin
DBV39_RS10900 2389069..2389368 - 300 WP_108623229.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DBV39_RS10905 2389709..2390847 + 1139 Protein_2074 IS630 family transposase -
DBV39_RS10910 2391285..2392679 + 1395 WP_108621548.1 IS1380 family transposase -
DBV39_RS10915 2393264..2394289 - 1026 WP_108623230.1 amidohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(3-96)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11189.73 Da        Isoelectric Point: 6.2954

>T104362 WP_108623229.1 NZ_CP028901:c2389368-2389069 [Algicoccus marinus]
MYSIRTTECFDDWFMGLRDIRARVRIQTRIDRLEMGNPGDSKSVGGGIVELRINYGPGYRVYYVQRGEVLVVLLCGGDKS
SQQNDIARAKEISSALDLE

Download         Length: 300 bp

>T104362 NZ_CP028901:c2389368-2389069 [Algicoccus marinus]
ATGTATTCGATTCGCACAACTGAATGCTTCGATGACTGGTTTATGGGGCTGCGTGATATCCGCGCTCGGGTACGCATTCA
GACTCGTATTGATCGCCTTGAAATGGGCAACCCTGGTGACAGCAAGTCTGTCGGGGGTGGAATTGTTGAATTGCGCATCA
ACTACGGACCTGGCTACAGGGTGTATTACGTTCAACGTGGTGAGGTGCTTGTAGTGCTGCTTTGTGGTGGGGATAAATCC
AGCCAGCAGAACGACATAGCGCGTGCCAAAGAAATTTCCAGCGCTCTTGATTTGGAGTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10726.24 Da        Isoelectric Point: 7.4027

>AT104362 WP_108621547.1 NZ_CP028901:c2389065-2388772 [Algicoccus marinus]
MKKTQTRPWDSAFHLRTEEEIAAYLDAALEEAGDDPKFIAHALGVIARAHGMSQLAKESGIKRESLYRALSGEGNPEFAT
IWKVIRALGIRLHAQPA

Download         Length: 294 bp

>AT104362 NZ_CP028901:c2389065-2388772 [Algicoccus marinus]
ATGAAAAAAACACAGACCCGGCCCTGGGATTCTGCCTTTCACCTTCGCACCGAAGAAGAAATTGCCGCCTATCTTGATGC
CGCACTTGAGGAGGCTGGCGACGATCCGAAGTTCATTGCCCATGCGCTCGGGGTCATCGCCCGTGCGCACGGGATGAGCC
AGCTTGCGAAGGAAAGCGGAATTAAGCGGGAGAGTCTTTACCGTGCTCTCTCGGGAGAAGGAAACCCTGAGTTTGCAACC
ATCTGGAAAGTGATTAGAGCCTTGGGTATTCGCTTGCACGCTCAGCCTGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References