Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 832207..832881 Replicon chromosome
Accession NZ_CP028901
Organism Algicoccus marinus strain HZ20

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DBV39_RS03655 Protein ID WP_108620389.1
Coordinates 832462..832881 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DBV39_RS03650 Protein ID WP_108620388.1
Coordinates 832207..832461 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DBV39_RS03630 827733..828377 + 645 WP_108620386.1 DUF4276 family protein -
DBV39_RS03635 828420..828662 + 243 WP_108623072.1 hypothetical protein -
DBV39_RS03640 828667..830385 + 1719 Protein_701 hypothetical protein -
DBV39_RS03645 830382..832091 + 1710 WP_108620387.1 hypothetical protein -
DBV39_RS03650 832207..832461 + 255 WP_108620388.1 plasmid stabilization protein Antitoxin
DBV39_RS03655 832462..832881 + 420 WP_108620389.1 type II toxin-antitoxin system VapC family toxin Toxin
DBV39_RS19685 832910..833191 + 282 WP_193853094.1 hypothetical protein -
DBV39_RS03665 833198..833386 + 189 WP_108620390.1 hypothetical protein -
DBV39_RS03670 833432..834172 - 741 WP_108620391.1 IS21-like element helper ATPase IstB -
DBV39_RS03675 834159..835664 - 1506 WP_108623073.1 IS21 family transposase -
DBV39_RS03680 835948..836217 + 270 WP_159078775.1 hypothetical protein -
DBV39_RS03685 836214..836405 + 192 WP_108620393.1 hypothetical protein -
DBV39_RS03690 836836..837513 + 678 WP_159078776.1 IS110 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15070.37 Da        Isoelectric Point: 4.5407

>T104361 WP_108620389.1 NZ_CP028901:832462-832881 [Algicoccus marinus]
MIILDTNVVSEAMKPEPDATVIAWLNEQAAETLYLSSITLAELLFGIGALPQGKRKNMLDRALTELLELFKDRVLPFDTD
AACHYADLAVTAKNGRRGFPTPDGYIAAIAASRGFMVASRDAAPYDAVGMAVINPWKDV

Download         Length: 420 bp

>T104361 NZ_CP028901:832462-832881 [Algicoccus marinus]
ATGATCATCCTGGATACCAATGTCGTTTCAGAGGCGATGAAGCCGGAACCGGATGCGACCGTAATAGCCTGGCTGAACGA
GCAGGCAGCGGAAACCTTGTATCTATCGAGCATTACCTTGGCCGAACTGCTGTTCGGCATCGGGGCGCTGCCGCAGGGCA
AGCGCAAGAACATGCTCGACCGTGCTCTTACCGAGCTGCTGGAGTTGTTCAAGGATCGAGTCTTGCCGTTCGACACGGAT
GCGGCCTGCCACTATGCGGACCTTGCCGTGACAGCCAAGAACGGCAGGCGTGGTTTCCCGACGCCAGACGGTTACATCGC
AGCCATTGCCGCATCGCGGGGCTTCATGGTGGCGTCGCGCGACGCCGCTCCCTATGATGCAGTTGGCATGGCCGTTATCA
ATCCCTGGAAAGACGTATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9233.57 Da        Isoelectric Point: 8.8262

>AT104361 WP_108620388.1 NZ_CP028901:832207-832461 [Algicoccus marinus]
MAILTVRNVPDDVHRALRVRAAEHGRSTEAEVREILAAAVKPEKRVRVGDALAAIGRKVGLTDEEFAVFENVRDKTPAKP
VSFD

Download         Length: 255 bp

>AT104361 NZ_CP028901:832207-832461 [Algicoccus marinus]
ATGGCAATCCTGACTGTAAGAAACGTGCCGGATGACGTGCATCGTGCTTTGCGTGTGCGGGCAGCCGAGCACGGTCGCAG
CACGGAAGCCGAGGTGCGCGAGATTCTGGCGGCAGCGGTCAAGCCAGAGAAGCGTGTGCGTGTAGGGGATGCGCTGGCCG
CCATCGGTCGCAAGGTTGGCCTGACTGACGAAGAATTTGCTGTCTTCGAGAATGTGCGCGACAAGACGCCGGCCAAGCCT
GTGAGTTTCGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References