Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 116178..116818 Replicon chromosome
Accession NZ_CP028901
Organism Algicoccus marinus strain HZ20

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DBV39_RS00555 Protein ID WP_108619889.1
Coordinates 116178..116585 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DBV39_RS00560 Protein ID WP_108619890.1
Coordinates 116585..116818 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DBV39_RS00530 111556..112698 + 1143 WP_108623005.1 paraquat-inducible protein A -
DBV39_RS00535 112751..114400 + 1650 WP_108619885.1 MCE family protein -
DBV39_RS00540 114397..115176 + 780 WP_159078699.1 PqiC family protein -
DBV39_RS00545 115415..115612 + 198 WP_108619887.1 hypothetical protein -
DBV39_RS00550 115692..115883 - 192 WP_108619888.1 hypothetical protein -
DBV39_RS00555 116178..116585 - 408 WP_108619889.1 tRNA(fMet)-specific endonuclease VapC Toxin
DBV39_RS00560 116585..116818 - 234 WP_108619890.1 antitoxin Antitoxin
DBV39_RS00565 117129..117407 + 279 WP_159078700.1 hypothetical protein -
DBV39_RS00570 117766..118566 + 801 WP_108619892.1 transposase -
DBV39_RS00575 118608..120371 - 1764 WP_108619893.1 acyl-CoA dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-116)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14793.02 Da        Isoelectric Point: 6.6406

>T104359 WP_108619889.1 NZ_CP028901:c116585-116178 [Algicoccus marinus]
MLRYMLDTNIVIYVLKRRPLAVLSTFNANASRMAISSITLAELIHGAEKSQRVSENLAAIEDFCSRLEVLPYGAKAAQHY
GAIRAALEKLGQPIGVNDLHIAGHARSEGLVLVTNNVAEFEHVPALELENWVNTA

Download         Length: 408 bp

>T104359 NZ_CP028901:c116585-116178 [Algicoccus marinus]
ATGTTGCGCTACATGCTCGACACCAACATCGTCATCTACGTGTTGAAGCGCCGCCCGCTCGCGGTGCTTTCCACGTTCAA
CGCCAACGCCAGTCGAATGGCCATCTCGTCAATCACCCTGGCCGAATTGATACACGGCGCCGAGAAAAGCCAACGCGTCA
GTGAGAACCTGGCGGCCATCGAGGACTTCTGCAGCCGCCTGGAGGTGCTGCCCTACGGTGCCAAGGCCGCCCAGCACTAC
GGCGCCATCCGCGCGGCCCTTGAAAAGCTCGGCCAACCCATCGGGGTGAATGACCTGCACATTGCGGGCCATGCCCGCAG
CGAAGGCTTGGTGCTGGTCACCAACAACGTCGCGGAGTTCGAACATGTGCCAGCGCTCGAACTTGAGAACTGGGTGAACA
CCGCTTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8773.98 Da        Isoelectric Point: 6.7241

>AT104359 WP_108619890.1 NZ_CP028901:c116818-116585 [Algicoccus marinus]
MSIGTVFINNRTQAVRLPLDVRLPEGVHKVEIRVKGHERIIAPLGQSWDSFFLDGPRVSDDFLPERASQHQPEREAL

Download         Length: 234 bp

>AT104359 NZ_CP028901:c116818-116585 [Algicoccus marinus]
ATGTCCATCGGTACCGTCTTCATCAACAACCGCACCCAAGCCGTCCGGCTGCCGTTGGACGTCCGTTTGCCCGAGGGCGT
CCACAAAGTCGAGATCCGCGTCAAAGGGCACGAGCGCATCATCGCGCCACTTGGTCAATCCTGGGACAGCTTCTTTCTGG
ACGGCCCGCGTGTGAGCGATGACTTTTTGCCCGAGCGTGCCTCTCAGCATCAGCCGGAGCGGGAAGCCCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References