Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 347442..348090 Replicon chromosome
Accession NZ_CP028899
Organism Stenotrophomonas maltophilia strain AB550

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag B7H26_RS01620 Protein ID WP_049403856.1
Coordinates 347442..347729 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag B7H26_RS01625 Protein ID WP_049403857.1
Coordinates 347788..348090 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7H26_RS01590 342703..343671 + 969 WP_046428093.1 bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor -
B7H26_RS01595 343668..344399 + 732 WP_049405470.1 type III pantothenate kinase -
B7H26_RS01600 344409..345263 + 855 WP_049405472.1 SPOR domain-containing protein -
B7H26_RS01610 345464..346588 - 1125 WP_080281819.1 hypothetical protein -
B7H26_RS23065 346611..347210 - 600 WP_141098883.1 hypothetical protein -
B7H26_RS01620 347442..347729 + 288 WP_049403856.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B7H26_RS01625 347788..348090 + 303 WP_049403857.1 putative addiction module antidote protein Antitoxin
B7H26_RS01630 348263..348664 - 402 WP_049403859.1 hypothetical protein -
B7H26_RS01635 349262..350032 + 771 WP_049403861.1 DUF3011 domain-containing protein -
B7H26_RS01640 350107..350556 - 450 WP_032956250.1 hypothetical protein -
B7H26_RS01645 350831..351751 + 921 WP_049403863.1 arginase -
B7H26_RS01650 351912..352049 + 138 WP_014035659.1 entericidin A/B family lipoprotein -
B7H26_RS01655 352253..352474 + 222 WP_004153772.1 CsbD family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-95)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10784.40 Da        Isoelectric Point: 10.6596

>T104357 WP_049403856.1 NZ_CP028899:347442-347729 [Stenotrophomonas maltophilia]
MKIQRTRQFATWIDALKDVTARARILARIGRLAEGQPGDHRYLGDGISELRIDAGPGYRLYYTQRGRQLLILLVGGDKSS
QQRDIEKAREIAFAL

Download         Length: 288 bp

>T104357 NZ_CP028899:347442-347729 [Stenotrophomonas maltophilia]
ATGAAGATCCAGCGTACCCGTCAGTTCGCGACATGGATTGACGCTCTCAAGGACGTAACTGCACGCGCTCGCATCCTGGC
TCGCATCGGTCGGCTCGCCGAAGGCCAGCCGGGTGATCACCGCTATCTGGGGGACGGTATTTCCGAACTGCGTATCGATG
CAGGGCCGGGCTACCGCCTGTACTACACCCAGCGCGGCAGGCAGTTGCTGATTCTTTTGGTCGGAGGTGACAAAAGCTCA
CAGCAACGCGATATCGAAAAGGCCAGGGAGATTGCATTTGCCCTGTGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10679.25 Da        Isoelectric Point: 9.0171

>AT104357 WP_049403857.1 NZ_CP028899:347788-348090 [Stenotrophomonas maltophilia]
MATKKKVELKAFNVAEHLRTPEEMAAYLDACIDESDGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FATILKVTRALGVRLHASAA

Download         Length: 303 bp

>AT104357 NZ_CP028899:347788-348090 [Stenotrophomonas maltophilia]
ATGGCCACTAAGAAAAAAGTCGAACTCAAAGCATTTAATGTGGCCGAACATCTTCGGACACCCGAAGAAATGGCCGCCTA
TCTCGACGCCTGCATCGACGAAAGCGACGGCGATTCCGCGTTCATCGCCAAGGCGCTCGGCGACATCGCGCGCGCTCAGG
GTATGAGCAAGGTTGCGCGCGCGGCGGGCCTGTCGCGCGAGAGTCTTTACCGCGCACTGTCCGGTGAGCGCAGCCCTGAT
TTCGCGACCATCCTGAAGGTGACCCGGGCCCTGGGTGTGCGATTGCACGCCAGCGCGGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References