Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1175948..1176458 Replicon chromosome
Accession NZ_CP028897
Organism Dongshaea marina strain DM2

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag DB847_RS05855 Protein ID WP_108649852.1
Coordinates 1175948..1176208 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag DB847_RS05860 Protein ID WP_108649853.1
Coordinates 1176201..1176458 (-) Length 86 a.a.

Genomic Context

DB847_RS05815DB847_RS05820DB847_RS05825DB847_RS05880DB847_RS05885DB847_RS05830DB847_RS05835DB847_RS05840DB847_RS05845DB847_RS05850DB847_RS05855DB847_RS05860DB847_RS05865DB847_RS05875DB847_RS05890DB847_RS05895
Location: 1171240..1172112 (873 bp)
Type: Others
Protein ID: WP_108649844.1
Location: 1172120..1172665 (546 bp)
Type: Others
Protein ID: WP_108649845.1
Location: 1172688..1173473 (786 bp)
Type: Others
Protein ID: WP_108649846.1
Location: 1178329..1178661 (333 bp)
Type: Others
Protein ID: WP_108649857.1
Location: 1178738..1179157 (420 bp)
Type: Others
Protein ID: WP_108649858.1
Location: 1173478..1173774 (297 bp)
Type: Others
Protein ID: WP_108649847.1
Location: 1173833..1174492 (660 bp)
Type: Others
Protein ID: WP_108649848.1
Location: 1174517..1174924 (408 bp)
Type: Others
Protein ID: WP_108649849.1
Location: 1174908..1175216 (309 bp)
Type: Others
Protein ID: WP_108649850.1
Location: 1175327..1175866 (540 bp)
Type: Others
Protein ID: WP_108649851.1
Location: 1175948..1176208 (261 bp)
Type: Toxin
Protein ID: WP_108649852.1
Location: 1176201..1176458 (258 bp)
Type: Antitoxin
Protein ID: WP_108649853.1
Location: 1176566..1176895 (330 bp)
Type: Others
Protein ID: WP_159084420.1
Location: 1177422..1178219 (798 bp)
Type: Others
Protein ID: WP_108649856.1
Location: 1179361..1180170 (810 bp)
Type: Others
Protein ID: WP_108649859.1
Location: 1180170..1181360 (1191 bp)
Type: Others
Protein ID: WP_108649860.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DB847_RS058151171240..1172112+873WP_108649844.1glucose-1-phosphate thymidylyltransferase RfbA-
DB847_RS058201172120..1172665+546WP_108649845.1dTDP-4-dehydrorhamnose 3,5-epimerase-
DB847_RS058251172688..1173473+786WP_108649846.1glycosyltransferase family 2 protein-
DB847_RS058301173478..1173774-297WP_108649847.1YciI family protein-
DB847_RS058351173833..1174492-660WP_108649848.1ribose-5-phosphate isomerase RpiA-
DB847_RS058401174517..1174924-408WP_108649849.1HI0074 family nucleotidyltransferase substrate-binding subunit-
DB847_RS058451174908..1175216-309WP_108649850.1nucleotidyltransferase domain-containing protein-
DB847_RS058501175327..1175866-540WP_108649851.1septation protein A-
DB847_RS058551175948..1176208-261WP_108649852.1Txe/YoeB family addiction module toxinToxin
DB847_RS058601176201..1176458-258WP_108649853.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
DB847_RS058651176566..1176895-330WP_159084420.1helix-hairpin-helix domain-containing protein-
DB847_RS058751177422..1178219-798WP_108649856.1alpha/beta hydrolase-
DB847_RS058801178329..1178661+333WP_108649857.1helix-turn-helix transcriptional regulator-
DB847_RS058851178738..1179157+420WP_108649858.1acyl-CoA thioesterase-
DB847_RS058901179361..1180170-810WP_108649859.1tryptophan synthase subunit alpha-
DB847_RS058951180170..1181360-1191WP_108649860.1tryptophan synthase subunit beta-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10348.81 Da        Isoelectric Point: 8.9903

>T104353 WP_108649852.1 NZ_CP028897:c1176208-1175948 [Dongshaea marina]
MNRQLAWTDEAWNSYIYWQGQDRKTLKRINKLIDAAKRSPFEGIGKPEPLKENLSGCWSRRITDEHRLVYIVDDLYLTIL
SCRYHY

Download         Length: 261 bp

>T104353 NZ_CP028897:c1176208-1175948 [Dongshaea marina]
ATGAATAGACAACTGGCATGGACTGATGAAGCCTGGAACTCATACATCTACTGGCAGGGTCAAGATAGAAAGACTCTCAA
GCGGATCAACAAACTCATAGATGCAGCCAAACGCAGTCCATTTGAGGGAATCGGAAAACCTGAGCCGCTTAAAGAAAACC
TGAGTGGCTGCTGGTCGCGGCGTATTACAGATGAGCATCGCCTGGTTTACATCGTTGATGATCTTTATCTCACCATCCTC
TCCTGCCGTTACCACTATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9497.65 Da        Isoelectric Point: 4.7640

>AT104353 WP_108649853.1 NZ_CP028897:c1176458-1176201 [Dongshaea marina]
MRVVSYTDARGNLKQVLDNVVEDADYTVITRRNADDAVVMSLESFNSLMETVHLLKSPANASHLERSLAQYKSGQAKVKD
LLDDE

Download         Length: 258 bp

>AT104353 NZ_CP028897:c1176458-1176201 [Dongshaea marina]
ATGCGGGTAGTCTCATATACAGATGCCAGAGGCAATCTCAAGCAGGTCTTAGACAATGTGGTCGAAGATGCTGATTACAC
AGTGATAACACGCCGTAATGCTGATGATGCCGTAGTTATGTCTCTTGAATCATTTAACAGCCTGATGGAAACTGTCCATC
TACTCAAGTCTCCAGCCAATGCTTCTCATTTAGAACGCTCACTGGCTCAGTACAAGTCAGGTCAGGCCAAAGTAAAAGAT
CTTCTCGACGATGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References