Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2288860..2289005 Replicon chromosome
Accession NZ_CP028850
Organism Klebsiella pneumoniae strain 3214

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2288896..2288998 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2288860..2289005 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DBX64_RS10860 2283990..2286050 + 2061 WP_004151449.1 oligopeptidase B -
DBX64_RS10865 2286054..2286713 - 660 WP_002911407.1 exodeoxyribonuclease X -
DBX64_RS10870 2286792..2287022 - 231 WP_002911406.1 DNA polymerase III subunit theta -
DBX64_RS10875 2287135..2287509 + 375 WP_004151448.1 CopC domain-containing protein YobA -
DBX64_RS10880 2287513..2288382 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
DBX64_RS10885 2288399..2288737 + 339 WP_002911404.1 YebY family protein -
- 2288860..2289005 - 146 - - Antitoxin
- 2288896..2288998 + 103 - - Toxin
DBX64_RS10890 2289373..2289516 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
DBX64_RS10895 2289621..2290589 - 969 WP_014907334.1 VirK/YbjX family protein -
DBX64_RS10900 2290746..2291399 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
DBX64_RS10905 2291396..2291587 - 192 WP_002911395.1 YebW family protein -
DBX64_RS10910 2291685..2291924 - 240 WP_002911393.1 YebV family protein -
DBX64_RS10915 2292040..2293473 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T104300 NZ_CP028850:2288896-2288998 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT104300 NZ_CP028850:c2289005-2288860 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References