Detailed information of TA system TA104245

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 5035831..5036336
• Replicon: chromosome
• Accession: NZ_CP028826
• Organism: Pseudomonas fluorescens strain MS82

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: DBV33_RS22850
• Protein ID: WP_108563191.1
• Coordinates: 5036082..5036336 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: DBV33_RS22845
• Protein ID: WP_108563190.1
• Coordinates: 5035831..5036085 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DBV33_RS22820	5031166..5031531	+	366	WP_108563187.1	hypothetical protein	-
DBV33_RS22825	5031556..5032302	-	747	WP_085655292.1	hypothetical protein	-
DBV33_RS22830	5032422..5032775	+	354	WP_085606881.1	hypothetical protein	-
DBV33_RS22835	5032896..5033642	+	747	WP_108563188.1	hypothetical protein	-
DBV33_RS22840	5033714..5035633	+	1920	WP_108563189.1	alkaline phosphatase family protein	-
DBV33_RS22845	5035831..5036085	+	255	WP_108563190.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
DBV33_RS22850	5036082..5036336	+	255	WP_108563191.1	Txe/YoeB family addiction module toxin	Toxin
DBV33_RS22855	5036330..5037517	-	1188	WP_108563192.1	aspartate aminotransferase family protein	-
DBV33_RS22860	5037620..5038525	+	906	WP_007956710.1	LysR family transcriptional regulator	-
DBV33_RS22865	5038600..5039124	+	525	WP_108563193.1	hypothetical protein	-
DBV33_RS22870	5039298..5040002	+	705	WP_108563194.1	hypothetical protein	-
DBV33_RS22875	5040071..5040562	-	492	WP_007956714.1	RidA family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 9938.66 Da
• Isoelectric Point: 10.3206

>T104245 WP_108563191.1 NZ_CP028826:5036082-5036336 [Pseudomonas fluorescens]
MKIQFTPTVWEDNLWLQQNDKTGLKRINLLIKAIQRQPFEGLGKPEPLKHNMSGFWSRRITAEHRLVYAIVDGKICVITC
RFHY

Nucleotide

• Length: 255 bp

>T104245 NZ_CP028826:5036082-5036336 [Pseudomonas fluorescens]
ATGAAAATCCAGTTCACGCCAACGGTCTGGGAAGACAACTTATGGCTTCAGCAAAACGATAAGACCGGTCTCAAACGAAT
CAATCTTCTGATCAAAGCGATCCAGCGCCAACCCTTTGAAGGCTTGGGTAAACCGGAGCCGCTCAAGCACAACATGAGCG
GCTTCTGGTCACGGCGGATAACTGCCGAGCATCGCCTGGTGTATGCAATCGTAGACGGCAAAATCTGCGTCATAACTTGC
AGATTTCACTACTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9449.87 Da
• Isoelectric Point: 4.8004

>AT104245 WP_108563190.1 NZ_CP028826:5035831-5036085 [Pseudomonas fluorescens]
MDTINYTTARAYLAETMDRVNEDCAPLLVTRQKGEPVVMMSLADYNALEETAYLLRSPANAERLIKSIGEMRAGKAKVRQ
LIEE

Nucleotide

• Length: 255 bp

>AT104245 NZ_CP028826:5035831-5036085 [Pseudomonas fluorescens]
ATGGACACTATCAACTACACCACAGCTCGTGCGTACTTGGCTGAAACCATGGATCGCGTGAATGAAGACTGCGCCCCACT
TCTGGTAACCCGTCAAAAAGGCGAGCCTGTAGTGATGATGTCTCTGGCCGATTATAACGCGCTGGAAGAAACGGCTTATC
TGCTGCGCTCTCCGGCCAATGCCGAGCGCTTGATCAAATCGATTGGCGAAATGCGCGCTGGAAAAGCCAAAGTCAGGCAA
CTGATTGAAGAATGA