Detailed information of TA system TA104243

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 3477219..3477687
• Replicon: chromosome
• Accession: NZ_CP028826
• Organism: Pseudomonas fluorescens strain MS82

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: DBV33_RS15705
• Protein ID: WP_011334552.1
• Coordinates: 3477403..3477687 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q3KBE7
• Locus tag: DBV33_RS15700
• Protein ID: WP_011334551.1
• Coordinates: 3477219..3477413 (+)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DBV33_RS15680	3472847..3473815	-	969	WP_108562301.1	Gfo/Idh/MocA family oxidoreductase	-
DBV33_RS15685	3473825..3474712	-	888	WP_108562303.1	Dyp-type peroxidase	-
DBV33_RS15690	3474769..3475803	-	1035	WP_108562305.1	AraC family transcriptional regulator	-
DBV33_RS15695	3476016..3476963	+	948	WP_108562307.1	transporter	-
DBV33_RS15700	3477219..3477413	+	195	WP_011334551.1	hypothetical protein	Antitoxin
DBV33_RS15705	3477403..3477687	+	285	WP_011334552.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10640.01 Da
• Isoelectric Point: 9.6587

>T104243 WP_011334552.1 NZ_CP028826:3477403-3477687 [Pseudomonas fluorescens]
MPLEWSDQALDDLADIIDYVEQYNSNASAALQHKVGAATQRLSSIPYGYRSGRAPGTREMVVNPNYLLVYRVNGRIKILT
LVHTRRQYPRTSST

Nucleotide

• Length: 285 bp

>T104243 NZ_CP028826:3477403-3477687 [Pseudomonas fluorescens]
CTGCCGCTTGAATGGAGCGATCAAGCTCTGGACGATCTGGCTGACATTATCGATTACGTTGAACAATACAACTCCAACGC
TTCAGCGGCTCTGCAGCACAAGGTTGGTGCAGCAACGCAAAGGCTTTCATCAATCCCTTATGGTTACCGATCCGGTCGAG
CGCCAGGCACTCGGGAAATGGTGGTCAATCCGAACTATCTGCTGGTCTATCGAGTGAACGGGCGCATCAAAATACTGACG
TTAGTCCACACCCGACGACAATACCCACGAACCTCATCTACATAA

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7590.45 Da
• Isoelectric Point: 4.8177

>AT104243 WP_011334551.1 NZ_CP028826:3477219-3477413 [Pseudomonas fluorescens]
MSILHSPFYSDFESEEEAESYDRWFRAKVQAVLDDPRPGIPHEEAMVRLDQLLEERRKNRRAAA

Nucleotide

• Length: 195 bp

>AT104243 NZ_CP028826:3477219-3477413 [Pseudomonas fluorescens]
ATGAGCATATTGCATTCCCCGTTTTACTCTGACTTCGAATCCGAAGAAGAGGCAGAGAGCTACGATCGCTGGTTTCGTGC
CAAGGTGCAGGCTGTACTGGATGATCCTCGCCCGGGCATTCCCCATGAGGAAGCCATGGTGCGGCTCGACCAACTATTAG
AAGAGAGACGCAAGAATCGACGCGCTGCCGCTTGA

Structures

Antitoxin

• AlphaFold DB: A0A345RRJ8