Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 1841326..1842365 Replicon chromosome
Accession NZ_CP028826
Organism Pseudomonas fluorescens strain MS82

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag DBV33_RS08560 Protein ID WP_108560305.1
Coordinates 1841326..1841901 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag DBV33_RS08565 Protein ID WP_108560308.1
Coordinates 1841898..1842365 (-) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DBV33_RS08535 1836653..1838641 + 1989 WP_108560302.1 heme lyase CcmF/NrfE family subunit -
DBV33_RS08540 1838638..1839174 + 537 WP_011333088.1 DsbE family thiol:disulfide interchange protein -
DBV33_RS08545 1839171..1839641 + 471 WP_064378637.1 cytochrome c-type biogenesis protein CcmH -
DBV33_RS08550 1839638..1840840 + 1203 WP_011333090.1 c-type cytochrome biogenesis protein CcmI -
DBV33_RS08555 1840866..1841273 + 408 WP_064378639.1 hypothetical protein -
DBV33_RS08560 1841326..1841901 - 576 WP_108560305.1 PIN domain-containing protein Toxin
DBV33_RS08565 1841898..1842365 - 468 WP_108560308.1 helix-turn-helix domain-containing protein Antitoxin
DBV33_RS08570 1842647..1843051 + 405 WP_085666700.1 type II toxin-antitoxin system HicB family antitoxin -
DBV33_RS08575 1843098..1844285 - 1188 WP_064378641.1 MFS transporter -
DBV33_RS08580 1844527..1845147 + 621 WP_108560311.1 hypothetical protein -
DBV33_RS08585 1845203..1846201 - 999 WP_011333096.1 sulfate ABC transporter substrate-binding protein -
DBV33_RS08590 1846306..1847130 - 825 WP_064594438.1 ion transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21519.80 Da        Isoelectric Point: 5.9178

>T104241 WP_108560305.1 NZ_CP028826:c1841901-1841326 [Pseudomonas fluorescens]
VRHSSFTALYDACVLYPAPLRDFLMWLALSGRFRARWTQEIHCEWKRNLLKNRPDLTMEQLDRTSGLMDQAIPDACVHDY
EDLIAGLSLPDCDDRHVLAAAIRCGASVIVTFNQKDFPCKALEPFGIEAQHPDEFVDNLLGLDAAAVVAAAQKQRRQLKM
PAMDVEPFLDLLQRQGLIKSVQALSSYHAIL

Download         Length: 576 bp

>T104241 NZ_CP028826:c1841901-1841326 [Pseudomonas fluorescens]
GTGAGGCATTCCTCTTTTACTGCTTTGTACGATGCATGCGTCTTGTACCCCGCCCCCTTGAGAGATTTCCTCATGTGGCT
TGCCCTCTCGGGGCGATTTCGGGCGCGATGGACCCAGGAGATTCACTGCGAATGGAAACGCAATCTGCTGAAGAACCGCC
CTGACCTGACGATGGAACAGCTGGATCGTACGTCCGGCCTGATGGATCAAGCGATACCCGACGCCTGTGTCCATGACTAT
GAAGACCTGATTGCCGGACTCAGCTTGCCCGACTGCGATGATCGTCATGTTCTGGCAGCGGCCATCCGTTGCGGCGCAAG
CGTGATAGTGACGTTCAACCAGAAAGACTTTCCCTGCAAAGCGCTGGAGCCTTTCGGCATCGAAGCGCAGCATCCGGACG
AGTTCGTCGACAACCTCTTGGGGCTTGATGCGGCAGCAGTGGTTGCAGCGGCCCAAAAACAGCGTCGGCAGCTGAAAATG
CCTGCCATGGACGTCGAACCCTTTCTTGATCTACTGCAACGACAAGGCCTGATTAAATCGGTCCAGGCACTCAGCAGTTA
TCACGCGATCCTTTAA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17285.70 Da        Isoelectric Point: 6.4962

>AT104241 WP_108560308.1 NZ_CP028826:c1842365-1841898 [Pseudomonas fluorescens]
MSTVIHPSISLPVEREVKAAIEGQRALAAYLATHFETQHIQIFDEQNEAHRVELPTSALRLLIDILAELAAGNAVQVVPV
HAELTTQEAADLLNVSRPHLIKLLESGELSYHKTGKHRRVRFADLMDYKNRRTTASEQAMALLAEQAQALRTGYE

Download         Length: 468 bp

>AT104241 NZ_CP028826:c1842365-1841898 [Pseudomonas fluorescens]
ATGTCGACCGTTATTCATCCCTCCATCAGCCTCCCCGTAGAACGCGAAGTCAAAGCCGCCATTGAAGGGCAGCGTGCCCT
GGCCGCTTACCTTGCGACCCATTTCGAGACTCAGCACATCCAAATTTTCGACGAGCAGAATGAAGCTCATCGCGTTGAAC
TGCCCACCTCGGCCCTGCGTCTGCTGATCGACATTCTGGCGGAGCTGGCAGCCGGCAACGCGGTACAGGTCGTACCGGTG
CATGCCGAATTGACGACCCAGGAAGCCGCGGACCTGCTCAACGTCTCACGTCCACACCTCATAAAACTGCTGGAAAGCGG
CGAGTTGTCCTACCACAAAACAGGCAAGCACCGACGTGTGCGCTTTGCCGATCTGATGGACTATAAGAACCGGCGCACCA
CCGCCAGCGAGCAGGCAATGGCGCTTCTCGCAGAGCAAGCTCAGGCGTTAAGGACAGGATACGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References