Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2916905..2917424 Replicon chromosome
Accession NZ_CP028808
Organism Burkholderia contaminans strain SK875

Toxin (Protein)


Gene name relE Uniprot ID A0A1E3FLI5
Locus tag SK875_RS30545 Protein ID WP_039349649.1
Coordinates 2917143..2917424 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4V2WFY1
Locus tag SK875_RS30540 Protein ID WP_039349647.1
Coordinates 2916905..2917153 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SK875_RS30530 2914337..2915527 + 1191 WP_039349643.1 2-methylaconitate cis-trans isomerase PrpF -
SK875_RS30535 2915711..2916763 + 1053 WP_039349645.1 CoA transferase -
SK875_RS30540 2916905..2917153 + 249 WP_039349647.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
SK875_RS30545 2917143..2917424 + 282 WP_039349649.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SK875_RS30550 2917542..2917985 - 444 WP_011353771.1 PaaI family thioesterase -
SK875_RS30555 2918255..2919874 + 1620 WP_039349654.1 Tar ligand binding domain-containing protein -
SK875_RS30560 2919847..2920956 - 1110 WP_039349656.1 AGE family epimerase/isomerase -
SK875_RS30565 2921071..2921769 + 699 WP_039349658.1 MgtC/SapB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-78)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10986.88 Da        Isoelectric Point: 10.7091

>T104229 WP_039349649.1 NZ_CP028808:2917143-2917424 [Burkholderia contaminans]
MTFELAFLEPALKEWKKLDRTVRDQFKSRLAERLENPRIPSAKLQGHPDRYKIKLRSVGYRLVYEVRDSEVLVLVVAVGR
RERDAVYLAAMKR

Download         Length: 282 bp

>T104229 NZ_CP028808:2917143-2917424 [Burkholderia contaminans]
ATGACCTTTGAGCTTGCCTTTCTCGAACCTGCTCTGAAAGAGTGGAAGAAGCTCGATCGCACCGTTCGCGATCAGTTCAA
ATCCCGGCTCGCCGAGCGGCTCGAGAATCCTCGAATACCGTCCGCGAAGCTGCAGGGTCATCCGGACCGCTACAAGATCA
AGCTGCGCAGCGTCGGCTATCGGCTCGTGTACGAAGTGCGCGATTCGGAAGTGCTCGTACTGGTCGTGGCGGTCGGTCGA
CGCGAGCGCGATGCTGTCTATCTTGCCGCGATGAAGCGTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9031.44 Da        Isoelectric Point: 5.6792

>AT104229 WP_039349647.1 NZ_CP028808:2916905-2917153 [Burkholderia contaminans]
MPHTILANVTASVSELKRNPMGTVAAGEGFPVAILNHNEPAFYCIPAKTWEAMVERLEDIEDNALADKRAKEKVVKVKLN
DL

Download         Length: 249 bp

>AT104229 NZ_CP028808:2916905-2917153 [Burkholderia contaminans]
ATGCCTCATACCATTCTGGCCAACGTTACGGCGAGCGTTTCGGAACTGAAGCGGAATCCGATGGGCACGGTCGCGGCAGG
AGAGGGTTTCCCGGTCGCGATCCTGAATCACAACGAACCCGCGTTCTATTGCATCCCGGCGAAGACCTGGGAGGCGATGG
TCGAACGCCTTGAAGATATCGAAGACAACGCGTTGGCCGACAAGCGCGCCAAGGAGAAGGTCGTCAAGGTCAAGCTGAAT
GACCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1E3FLI5

Antitoxin

Source ID Structure
AlphaFold DB A0A4V2WFY1

References