Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 3006866..3007396 Replicon chromosome
Accession NZ_CP028807
Organism Burkholderia contaminans strain SK875

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag SK875_RS14530 Protein ID WP_076841743.1
Coordinates 3006866..3007129 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag SK875_RS14535 Protein ID WP_076841742.1
Coordinates 3007151..3007396 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SK875_RS14510 3003725..3004474 + 750 WP_039358610.1 uroporphyrinogen-III C-methyltransferase -
SK875_RS14515 3004471..3004848 + 378 WP_039358613.1 cobalamin biosynthesis protein -
SK875_RS14520 3004886..3005488 + 603 WP_039358616.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
SK875_RS14525 3005491..3006795 + 1305 WP_039358619.1 cobyrinate a,c-diamide synthase -
SK875_RS14530 3006866..3007129 - 264 WP_076841743.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SK875_RS14535 3007151..3007396 - 246 WP_076841742.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
SK875_RS14540 3007513..3008676 - 1164 WP_039358627.1 amidohydrolase -
SK875_RS14545 3009017..3010084 + 1068 WP_039358630.1 hypothetical protein -
SK875_RS14550 3010098..3010337 + 240 Protein_2737 nucleotidyltransferase -
SK875_RS14555 3010386..3010802 - 417 Protein_2738 type II toxin-antitoxin system VapC family toxin -
SK875_RS14560 3010799..3011065 - 267 WP_046196769.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
SK875_RS14565 3011315..3012331 - 1017 WP_039358635.1 acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-82)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10242.66 Da        Isoelectric Point: 6.0735

>T104225 WP_076841743.1 NZ_CP028807:c3007129-3006866 [Burkholderia contaminans]
MAELDLEDIWRDTVGRGSLKQTDLYHRDLIGTMEALARGEKVGRTCIVRDGYFRYAVGSHVVFYRETEYTIDLIRVLHQR
MDIEQHL

Download         Length: 264 bp

>T104225 NZ_CP028807:c3007129-3006866 [Burkholderia contaminans]
CTGGCCGAACTCGATCTCGAAGACATTTGGCGCGATACCGTCGGGCGTGGGTCGCTCAAGCAAACCGACCTTTACCACCG
CGATCTGATCGGAACCATGGAAGCGCTGGCGCGCGGTGAAAAGGTCGGCCGGACTTGCATTGTTCGCGATGGATATTTCC
GGTACGCCGTGGGCTCCCACGTCGTGTTCTATCGTGAAACGGAATACACGATCGATTTGATTCGGGTCCTGCATCAACGC
ATGGACATCGAACAACATCTGTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9021.01 Da        Isoelectric Point: 5.6864

>AT104225 WP_076841742.1 NZ_CP028807:c3007396-3007151 [Burkholderia contaminans]
MSQNASVSRRDHFAELVDTQVQSEQYGSASDVERTGLRLLESRDMQVRALQEALKAGEVSGALRPFDREAFLARMRAAHD
G

Download         Length: 246 bp

>AT104225 NZ_CP028807:c3007396-3007151 [Burkholderia contaminans]
ATGTCGCAAAACGCATCCGTTTCCCGGCGCGACCACTTTGCCGAACTCGTCGATACCCAAGTGCAATCGGAACAATACGG
TTCCGCAAGCGACGTCGAACGAACCGGTTTGCGGCTTCTCGAATCACGCGACATGCAGGTGCGCGCGTTGCAGGAAGCGT
TGAAGGCCGGGGAGGTATCGGGAGCACTCAGGCCATTCGACCGCGAGGCCTTCCTGGCCCGCATGCGGGCCGCGCATGAC
GGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References