Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 914727..916462 Replicon chromosome
Accession NZ_CP028800
Organism Acinetobacter junii strain WCHAJ59

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag CDG57_RS04670 Protein ID WP_087540866.1
Coordinates 914727..915383 (+) Length 219 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag CDG57_RS04675 Protein ID WP_087540868.1
Coordinates 915383..916462 (+) Length 360 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDG57_RS04655 910504..911718 - 1215 WP_087540860.1 inovirus-type Gp2 protein -
CDG57_RS04660 912190..912456 - 267 WP_087540862.1 AlpA family phage regulatory protein -
CDG57_RS04665 912586..913806 - 1221 WP_137415198.1 hypothetical protein -
CDG57_RS04670 914727..915383 + 657 WP_087540866.1 DUF4433 domain-containing protein Toxin
CDG57_RS04675 915383..916462 + 1080 WP_087540868.1 macro domain-containing protein Antitoxin
CDG57_RS04680 916624..917556 + 933 WP_108565300.1 IS5 family transposase -
CDG57_RS04685 917657..918694 - 1038 WP_087541046.1 L,D-transpeptidase -
CDG57_RS04690 918879..919808 - 930 WP_005313773.1 IS5 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(18-218)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 219 a.a.        Molecular weight: 25602.21 Da        Isoelectric Point: 6.6549

>T104200 WP_087540866.1 NZ_CP028800:914727-915383 [Acinetobacter junii]
MAVRTYHDVLNPEKALIWRIVHRDNIPWILVNGLHCSNSTTQYAEWVKIGSPELIEKRQQHPVPVGTKGVLSDYIPFYFT
PFSPMLLNIKSGRGGVPQRDNDEIVILVSSLHHLYQQHIPFVFTNSHAYYQWTEFYTDLSNLDEIDWSILQTRDFKRDMD
DPAKFERYQAEALIYQHCPAEALLGMMCYNESVKSQLEYWLQQAKINIPVHVRRGVYF

Download         Length: 657 bp

>T104200 NZ_CP028800:914727-915383 [Acinetobacter junii]
TTGGCAGTGCGAACATATCATGATGTACTCAATCCTGAAAAAGCCCTGATTTGGCGGATCGTGCATCGTGACAATATCCC
TTGGATATTGGTGAATGGCTTACATTGCAGTAATAGCACAACACAATATGCGGAATGGGTGAAAATCGGTAGTCCTGAGT
TGATTGAAAAACGCCAACAACATCCTGTTCCTGTTGGAACTAAAGGCGTATTGAGCGACTATATTCCATTTTATTTCACA
CCATTTTCACCAATGCTACTGAATATAAAAAGTGGCCGTGGCGGTGTGCCTCAACGTGACAATGATGAAATTGTGATTTT
GGTTTCTAGTTTGCATCACTTATACCAACAACACATTCCTTTTGTATTTACCAATAGTCATGCTTACTACCAATGGACTG
AATTTTATACGGATTTATCCAACCTTGATGAAATTGATTGGTCTATCTTACAGACAAGAGATTTTAAACGGGATATGGAT
GACCCTGCGAAATTTGAACGCTACCAAGCAGAAGCTTTGATTTACCAGCATTGTCCTGCGGAAGCATTATTGGGGATGAT
GTGCTACAATGAAAGCGTCAAAAGTCAATTAGAATATTGGTTGCAACAAGCAAAAATTAATATTCCTGTGCATGTTCGAC
GTGGAGTGTATTTCTAA

Antitoxin


Download         Length: 360 a.a.        Molecular weight: 40807.98 Da        Isoelectric Point: 6.3966

>AT104200 WP_087540868.1 NZ_CP028800:915383-916462 [Acinetobacter junii]
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPKNMAAYSQACKASQVATGRMFVTETGELMGARWIINFPTK
QHWRDKSKIEWIEEGLQELKQFIIEHQVKSIAIPPLGAGNGGLNWHEVKTKIEAALSDLDQVEIVIFEPTAQYQNVAKKT
GVSHLTPARAMIAELVRRYWVLGIECSLLEIQKLAWFLQRAIEQKQLPNELKLNFQANFYGPYAANLEHLLNAMDGSYLK
SDKRIPDCDPLDVIWFNDQQKSNVQTYLLSEAKNYMVALEEAATLIEGFESPFGMELLATVDWLIYKEGYQPNVKAIQQG
LANWSAGERWAQRKLNLFKPEHIQYALDKLNHFESINTV

Download         Length: 1080 bp

>AT104200 NZ_CP028800:915383-916462 [Acinetobacter junii]
ATGATTCGATATACAACAGGTAATCTACTTGATGCCCCTGTAGAAGCATTGGTGAACACTGTCAATACCGTTGGTGTAAT
GGGGAAAGGCATTGCCTTAATGTTCAAGGAACGCTTCCCAAAAAACATGGCAGCTTATAGTCAAGCATGTAAAGCGAGTC
AAGTTGCGACAGGCAGAATGTTTGTGACTGAAACGGGCGAATTGATGGGCGCACGTTGGATCATTAACTTTCCAACTAAA
CAACATTGGCGTGACAAATCTAAAATCGAATGGATTGAAGAGGGGTTACAAGAACTCAAACAATTCATTATTGAACATCA
AGTCAAATCGATTGCTATTCCGCCACTCGGCGCTGGTAACGGTGGATTAAACTGGCATGAAGTAAAAACCAAAATTGAAG
CTGCATTATCAGACTTAGATCAGGTTGAGATTGTTATTTTTGAACCAACTGCCCAATATCAAAATGTAGCAAAGAAAACA
GGTGTATCACACTTGACACCTGCACGCGCCATGATTGCCGAATTAGTTCGTCGTTATTGGGTTTTGGGAATAGAATGTAG
TTTGTTGGAAATTCAAAAACTAGCATGGTTTTTACAGCGGGCCATTGAACAAAAACAATTACCTAATGAGTTAAAACTAA
ACTTTCAGGCAAACTTTTATGGTCCTTATGCTGCCAATTTAGAACATTTATTGAATGCAATGGATGGTAGCTATCTAAAG
TCGGATAAGCGTATTCCTGATTGTGATCCTTTAGATGTGATTTGGTTCAATGATCAACAGAAGTCTAATGTGCAAACCTA
CCTTTTGAGTGAGGCTAAAAACTATATGGTTGCTTTAGAAGAAGCAGCAACATTAATAGAAGGCTTCGAATCACCATTTG
GTATGGAATTGTTAGCGACTGTAGATTGGCTTATTTATAAGGAAGGTTATCAACCTAATGTTAAGGCGATTCAGCAAGGT
TTGGCCAACTGGTCAGCTGGAGAGCGTTGGGCACAACGTAAATTGAACTTATTTAAGCCAGAGCACATTCAATATGCTTT
GGATAAACTAAATCATTTTGAATCTATAAATACTGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References