Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3046166..3046311 Replicon chromosome
Accession NZ_CP028797
Organism Klebsiella pneumoniae strain WCHKP040035

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3046173..3046275 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3046166..3046311 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6M51_RS17085 3041698..3043131 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
C6M51_RS17090 3043247..3043486 + 240 WP_002911393.1 YebV family protein -
C6M51_RS17095 3043584..3043775 + 192 WP_002911395.1 YebW family protein -
C6M51_RS17100 3043772..3044425 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
C6M51_RS17105 3044660..3045550 + 891 WP_085353163.1 VirK/YbjX family protein -
C6M51_RS17110 3045940..3046131 + 192 WP_004175432.1 hypothetical protein -
- 3046166..3046311 + 146 - - Antitoxin
- 3046173..3046275 - 103 - - Toxin
C6M51_RS17115 3046434..3046775 - 342 WP_015874944.1 YebY family protein -
C6M51_RS17120 3046789..3047658 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
C6M51_RS17125 3047662..3048036 - 375 WP_004151448.1 CopC domain-containing protein YobA -
C6M51_RS17130 3048149..3048379 + 231 WP_002911406.1 DNA polymerase III subunit theta -
C6M51_RS17135 3048458..3049117 + 660 WP_101963436.1 exodeoxyribonuclease X -
C6M51_RS17140 3049121..3051181 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T104183 NZ_CP028797:c3046275-3046173 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT104183 NZ_CP028797:3046166-3046311 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References