Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1937692..1937837 Replicon chromosome
Accession NZ_CP028787
Organism Klebsiella pneumoniae strain SCKP020049

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1937728..1937830 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1937692..1937837 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLQ68_RS11160 1932822..1934882 + 2061 WP_004151449.1 oligopeptidase B -
CLQ68_RS11165 1934886..1935545 - 660 WP_021440386.1 exodeoxyribonuclease X -
CLQ68_RS11170 1935624..1935854 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CLQ68_RS11175 1935967..1936341 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CLQ68_RS11180 1936345..1937214 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
CLQ68_RS11185 1937231..1937569 + 339 WP_002911404.1 YebY family protein -
- 1937692..1937837 - 146 - - Antitoxin
- 1937728..1937830 + 103 - - Toxin
CLQ68_RS28035 1938206..1938349 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CLQ68_RS11195 1938454..1939422 - 969 WP_004151446.1 VirK/YbjX family protein -
CLQ68_RS11200 1939579..1940232 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
CLQ68_RS11205 1940229..1940420 - 192 WP_002911395.1 YebW family protein -
CLQ68_RS11210 1940518..1940757 - 240 WP_002911393.1 YebV family protein -
CLQ68_RS11215 1940873..1942306 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1872891..1955234 82343


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T104131 NZ_CP028787:1937728-1937830 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT104131 NZ_CP028787:c1937837-1937692 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References