Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1925716..1925860 Replicon chromosome
Accession NZ_CP028783
Organism Klebsiella pneumoniae subsp. pneumoniae strain SCKP020046

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1925752..1925854 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1925716..1925860 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLQ69_RS11170 1920846..1922906 + 2061 WP_004151449.1 oligopeptidase B -
CLQ69_RS11175 1922910..1923569 - 660 WP_002911407.1 exodeoxyribonuclease X -
CLQ69_RS11180 1923648..1923878 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CLQ69_RS11185 1923991..1924365 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CLQ69_RS11190 1924369..1925238 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
CLQ69_RS11195 1925252..1925593 + 342 WP_015874944.1 YebY family protein -
- 1925716..1925860 - 145 - - Antitoxin
- 1925752..1925854 + 103 - - Toxin
CLQ69_RS11200 1925987..1926346 - 360 WP_077253379.1 tyrosine-type recombinase/integrase -
CLQ69_RS11205 1926345..1926824 + 480 WP_032419797.1 lysis protein -
CLQ69_RS11210 1927279..1927474 + 196 Protein_1904 DNA polymerase V -
CLQ69_RS11215 1927613..1929118 + 1506 WP_020956680.1 hypothetical protein -
CLQ69_RS11220 1929368..1929796 - 429 WP_032419788.1 type II toxin-antitoxin system PemK/MazF family toxin -
CLQ69_RS11225 1929806..1930087 - 282 WP_032419786.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T104113 NZ_CP028783:1925752-1925854 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT104113 NZ_CP028783:c1925860-1925716 [Klebsiella pneumoniae subsp. pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References