Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2282820..2283088 Replicon chromosome
Accession NZ_CP028770
Organism Escherichia coli strain A4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2282948..2283050 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2282820..2283088 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY55_RS10685 2279374..2280036 - 663 WP_000944256.1 exodeoxyribonuclease X -
AOY55_RS10690 2280059..2280715 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
AOY55_RS10695 2280817..2281047 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AOY55_RS10700 2281186..2281560 + 375 WP_000168747.1 CopC domain-containing protein YobA -
AOY55_RS10705 2281564..2282436 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
AOY55_RS10710 2282449..2282790 + 342 WP_000976472.1 YebY family protein -
- 2282820..2283088 - 269 - - Antitoxin
- 2282948..2283050 + 103 - - Toxin
AOY55_RS10715 2283185..2283841 + 657 WP_000812742.1 protein-serine/threonine phosphatase -
AOY55_RS10720 2283842..2284033 - 192 WP_001317886.1 YebW family protein -
AOY55_RS10725 2284138..2284374 - 237 WP_001295499.1 YebV family protein -
AOY55_RS10730 2284492..2285931 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T104040 NZ_CP028770:2282948-2283050 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT104040 NZ_CP028770:c2283088-2282820 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References