Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2029124..2029395 Replicon chromosome
Accession NZ_CP028769
Organism Escherichia coli strain A5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2029254..2029357 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2029124..2029395 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY56_RS09720 2025679..2026341 - 663 WP_000944256.1 exodeoxyribonuclease X -
AOY56_RS09725 2026365..2027021 - 657 WP_087599297.1 carbon-nitrogen hydrolase family protein YobB -
AOY56_RS09730 2027123..2027353 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AOY56_RS09735 2027492..2027866 + 375 WP_000204699.1 CopC domain-containing protein YobA -
AOY56_RS09740 2027870..2028742 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
AOY56_RS09745 2028755..2029096 + 342 WP_000976492.1 YebY family protein -
- 2029124..2029395 - 272 - - Antitoxin
- 2029254..2029357 + 104 - - Toxin
AOY56_RS09750 2029492..2030148 + 657 WP_087599296.1 protein-serine/threonine phosphatase -
AOY56_RS09755 2030149..2030340 - 192 WP_001296140.1 YebW family protein -
AOY56_RS09760 2030445..2030681 - 237 WP_001295499.1 YebV family protein -
AOY56_RS09765 2030799..2032238 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T104014 NZ_CP028769:2029254-2029357 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT104014 NZ_CP028769:c2029395-2029124 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References